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2012年11月 Nature Medicine G' H0 w4 b( V0 K
, R- e) D% {9 ~9 d! KIn this issue, Andrew Weng and his colleagues uncover a new : }. _. W7 C" w$ |# S
mechanism by which oncogenes regulate leukemia stem cells. Notch-driven
6 Q7 J" m; g6 w4 ]/ T$ \+ V3 Jinactivation of PKCθ attenuates the accumulation of - D" `, X% @5 |" h
reactive oxygen species to lower oxidative stress in the stem cell population of $ n% j! K; P" V$ C
T cell acute lymphoblastic leukemia (ALL), contributing to tumorigenesis. The
" t: m- s% i5 @- A2 R; uimage shows an electron micrograph of erythrocytes and lymphocytes from a
( f2 R& D G1 |patient with ALL. Photo by Steve Gschmeissner/Science Photo Library.
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/ Z3 b1 `9 A: {/ s9 ~[hide][/hide] |
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发表于 2012-11-10 12:55
发表于 2012-11-12 16:35
