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2012年11月 Nature Medicine" E2 s: ^+ w F. W
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In this issue, Andrew Weng and his colleagues uncover a new
0 C' \& V* d$ n6 fmechanism by which oncogenes regulate leukemia stem cells. Notch-driven
! a, O5 P& E. Y$ F+ Q/ ^inactivation of PKCθ attenuates the accumulation of ' l- R& d& ^5 f- [* A7 |
reactive oxygen species to lower oxidative stress in the stem cell population of M3 l; ]; B8 b
T cell acute lymphoblastic leukemia (ALL), contributing to tumorigenesis. The ! K) d, b6 w. Z- @5 I: G4 q% t
image shows an electron micrograph of erythrocytes and lymphocytes from a 0 s# P1 w* d" t5 b' G' t
patient with ALL. Photo by Steve Gschmeissner/Science Photo Library. 2 L8 C4 d0 t% `9 `0 ^+ c
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发表于 2012-11-10 12:55
发表于 2012-11-12 16:35
