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2012年11月 Nature Medicine
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" g) L+ }# I- y" ^In this issue, Andrew Weng and his colleagues uncover a new ( N$ Q$ V7 L/ G2 E0 P. W
mechanism by which oncogenes regulate leukemia stem cells. Notch-driven
. X7 {! g: B# A5 Zinactivation of PKCθ attenuates the accumulation of & w) m, {" L% |* _2 E g/ @
reactive oxygen species to lower oxidative stress in the stem cell population of 4 W/ }* t3 @) ~; ?$ a
T cell acute lymphoblastic leukemia (ALL), contributing to tumorigenesis. The $ Q, I/ c9 u5 n
image shows an electron micrograph of erythrocytes and lymphocytes from a / p, N$ ~8 v1 x
patient with ALL. Photo by Steve Gschmeissner/Science Photo Library.
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发表于 2012-11-10 12:55
发表于 2012-11-12 16:35
