PDF电子书：PROTEIN ENGINEERING （2012）

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) R2 ?8 m  P9 `7 r( k! W8 D4 U! Q" aPROTEIN ENGINEERING
1 `8 ]7 l) `) O  REdited by Pravin Kaumaya
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& Y' e7 \) {! ~# h. I3 ~Copyright © 2012 InTech
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$ D7 n+ ?, P7 mContents
. f( P# ~: R" M0 G: v: F5 gPreface   IX
, k8 G% s. ]9 q; t5 S4 G4 jChapter 1   Structure-Functional Insight Into Transmembrane Helix Dimerization   1* ^% C. D9 J$ @8 i6 t$ K9 w
Eduard V. Bocharov, Konstantin V. Pavlov, Pavel E. Volynsky, Roman G. Efremov and Alexander S. 3 O2 T* f2 C& ~: Y! o
Arseniev# Z# D. I! C6 d, x$ j

" S' a$ z! B0 Q( NChapter 2    Protein Engineering Methods and Applications   33
9 h" p( B$ D! A; K" v! Z  uBurcu Turanli-Yildiz, Ceren Alkim and Z. Petek Cakar
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% b! u8 D% z, R3 C4 Z. W0 UChapter 3   Evolutionary Engineering of Artificial Proteins with Limited Sets of Primitive Amino
& d6 c1 x7 p" i! sAcids   59 Junko Tanaka, Hiroshi Yanagawa and Nobuhide Doi
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4 q5 ^$ t( |2 h% B' z2 B" y( ]* xChapter 4   Protein Engineering Applications on Industrially Important Enzymes:
! ^( b: O8 A6 H) Q5 e# a. k7 t; jCandida methylica FDH as a Case Study    75
# T) o5 d  f1 q9 r  V! NEmel Ordu and Nevin Gül Karagüler
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- Y& N* y: ~0 `* TChapter 5      Engineering High-Affinity T Cell Receptor/ Cytokine Fusions for Therapeutic 0 m' C7 U4 a* v3 X
Targeting    99 Jennifer D. Stone, Yiyuan Yin, Min Mo,
0 I0 _  Q/ j0 V2 g* dK. Scott Weber, David L. Donermeyer,2 C* X9 V8 ?& n  R- I7 x. {5 D
Paul M. Allen, Roy A. Mariuzza and David M. Kranz
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Chapter 6    Molecular Evolution Within7 v( N6 N( P$ N7 w) n9 U" s5 }7 ~
Protease Family C2, or Calpains    119
& J6 _. A& ]/ eLiudmila Lysenko and Nina Nemova! f1 C2 i7 \% L* N& g! ~3 [/ z+ \
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Chapter 7    FN3 Domain Engineering   1453 J( ^. Q5 ?+ p1 c
Steven Jacobs and Karyn O’Neil2 S: C4 E) t: j1 y; H8 y- s
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Chapter 8    Engineered Derivatives of
. K5 o& w( N' i" v& ~; xMaltose-Binding Protein   1637 R8 K5 `7 i; [# o
Paul D. Riggs! _5 [  O% z* e: a1 ~" A8 [8 z
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VI     Contents
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5 u6 J1 f4 D9 d& ]Chapter 9      Applications of Bioinformatics and Experimental Methods  to Intrinsic Disorder-Based & ]- |- l% m# z) b) g
Protein-Protein Interactions    181 Xiaolin Sun, William T. Jones and Vladimir N. Uversky
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Chapter 10     Protein Folding, Binding and Energy Landscape: A Synthesis   207
5 A# o0 a3 J- e0 k6 ?* a, Q0 [Shu-Qun Liu, Yue-Hui Xie, Xing-Lai Ji, Yan Tao, De-Yong Tan, Ke-Qin Zhang and Yun-Xin Fu
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1 ^0 \, Z( f' |$ g" o9 L$ I6 LChapter 11    Protein Engineering with Non-Natural Amino Acids   2533 J2 {6 L$ A; u' S) _8 n
Aijun Wang, Natalie Winblade Nairn, Marcello Marelli and Kenneth Grabstein/ j0 i4 Y/ n7 R/ `3 l
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Chapter 12    Generation of Xylose-Fermenting0 F' z# m! T3 Z
Saccharomyces Cerevisiae by Protein-Engineering    291
+ t5 x3 n* `7 ^5 D9 ^$ W  G* C7 aSeiya Watanabe and Keisuke Makino
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Chapter 13   In Silico Engineering of Proteins
: i2 E( l4 R7 C& [7 iThat Recognize Small Molecules    307 Sushil Kumar Mishra, Gabriel Demo, Jaroslav Koča and Michaela
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