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本帖最后由 细胞海洋 于 2013-2-21 10:11 编辑
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Book Title$ y( a4 n6 k! V i c
Stem Cell Engineering
* h* [1 ~+ D% Q) O5 NBook Subtitle
( G H7 ^ N, {' ~1 i% WPrinciples and Applications( I( n ^% d" y0 o
Copyright
; u" L& z7 D, z2011- O- W* s$ A$ P9 S* J8 M7 w2 C$ I
DOI2 Q% f$ d [- Y' E( O) b
10.1007/978-3-642-11865-4; |; t! J3 Z0 {% f; |
Print ISBN
7 H: K( g3 m( V' O7 ?978-3-642-11864-7) E, t# b" U/ z0 j
Online ISBN
8 n; [: I R; g6 Y% M* e2 P1 `5 t978-3-642-11865-4% h6 R# T3 R3 ~% X+ g4 L$ B
Publisher1 x6 b/ S4 w. t: D
Springer Berlin Heidelberg
& x6 e3 x7 C u) w/ w) s2 nCopyright Holder, H$ w+ j' d ]' w( Z) o
Springer-Verlag Berlin Heidelberg
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5 ~; Z* C3 X8 v" g0 V- Reviews Engineering Approaches in Stem Cell Research' F6 ?0 L( h2 R+ ~, D
- Provides a solid reference for researchers and advanced graduate student
9 l7 P I7 R4 n. h% r# BThe potential of stem cells for healing and disease prevention in all fields of medicine is tremendous and has revolutionized the high-tech biomedical research. In this book, many of the most prominent researchers discuss the challenging topics of stem cell engineering, for example: Ethical issues of stem cell research; technological challenges, stem cell growth and differentiation, therapeutic applications, bioreactors and bioprocesses, high throughput and microfluidic screening platforms, stem cell identification and sorting, intercellular signaling and engineered niches, novel approaches for embryonic and adult stem cell growth and differentiation, stem cells and drug discovery, screening platforms. Stem Cell Engineering offers valuable background and reference for both the public and professionals including industrial staffers, faculty, researchers, engineers, students and scientific journalists.
2 c5 T6 w/ }7 i' J- [Content Level » Research9 |1 [$ Y3 z9 c: Z, }
) g+ E5 o* `3 a! F/ AKeywords » bioreactors - cell expansion - differentiation - drug discovery - embryonic stem cell growth - stem cell growth" s" O! }6 i* L {
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Related subjects » Biomedical Engineering - Biotechnology - Cell Biology9 g B8 J, ]1 x i6 v
) e8 l/ i- V" EContents
% {% {3 p/ L4 Q' E4 \. o0 tPart I Instead of an Introduction – The Emperor’s New Legs
/ w+ _% ^5 D) c+ c, m/ g, }The Emperor’s New Body: Seeking for a Blueprint of Limb
! e. X* H) O9 S, Q. d. J7 WRegeneration in Humans . . . . . . . . . . . . . . . . . . . . . . . . . . 3! k( s7 z% w3 w: T# R% ]4 D0 u
Ilya Digel and Aysegül Temiz Artmann
2 ?6 @/ M* h; j: X0 YPart II Basics and Basic Research
! V9 b, N! J# {) j1 U% ^1 G+ YEngineering the Stem Cell Niche and the Differentiative Microand
1 s; Q5 M* \% U6 KMacroenvironment: Technologies and Tools for Applying! }; A1 g; G5 j9 M9 B& ^0 k
Biochemical, Physical and Structural Stimuli and Their Effects2 J4 B" w0 `3 ]& [% t ~/ i% d
on Stem Cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 410 |# ~$ j4 P; u& q- j6 J1 O3 A
Paolo Di Nardo, Marilena Minieri, and Arti Ahluwalia# r& M* z& h/ g. w h
Differentiation Potential of Adult Human Mesenchymal Stem Cells . . 61
6 w5 y% ], W; F. VEdda Tobiasch) ~+ y& b- c0 M1 X7 L# V
The Potential of Selectively Cultured Adult Stem Cells# k+ N/ m/ V) [
Re-implanted in Tissues . . . . . . . . . . . . . . . . . . . . . . . . . . . 791 _! D' O: v6 u8 Y. O5 e% a
Isgard S. Hueck, Martin Haas, Rita Finones, Jane Frimodig,+ }! \7 ?2 i; w% l0 A; A
and David A. Gough, d# j6 J) g! X$ x6 i; {3 B
Enhanced Cardiac Differentiation of Mouse Embryonic Stem
& H# }. n/ y; c; x% ^; DCells by Electrical Stimulation . . . . . . . . . . . . . . . . . . . . . . . 119: K* ` {- X! N, y5 j
Paul R. Bidez III, J. Yasha Kresh, Yen Wei, and Peter I. Lelkes
) f6 f% {2 A2 VThe Therapeutic Potential of ES-Derived Haematopoietic Cells . . . . . 1432 U2 O: S8 V& V
Sabrina Gordon-Keylock and Lesley Forrester
9 P L) _4 O, K. BGenetic Modification of Human Embryonic and Induced' K: ]5 S- q" @$ j7 N
Pluripotent Stem Cells: Viral and Non-viral Approaches . . . . . . . . . 159
9 N1 G6 s4 h4 ~# I/ C$ `1 |! n4 _Nicole M. Kane, Chris Denning, and Andrew H. Baker
+ w- T- P! D. p7 @0 FThe Immune Barriers of Cell Therapy with Allogenic Stem
, ]1 H& a5 X- o7 C8 i7 lCells of Embryonic Origin . . . . . . . . . . . . . . . . . . . . . . . . . 181
0 H: p8 e( h g& @/ `- c _Olivier Preynat-Seauve, Karl-Heinz Krause, and Jean Villard! g' ~- c. i6 c
xxxi' }. t: i6 d$ ~! K& s( o0 x
xxxii Contents
% M8 j6 t8 d8 q2 @% nReponses of Mesenchymal Stem Cells to Varying Oxygen' x' B8 w5 ?! o: k1 w
Availability In Vitro and In Vivo . . . . . . . . . . . . . . . . . . . . . . 199/ ~# {: K& r' x4 N3 b+ `5 ?7 s
Frank R. Kloss, Sarvpreet Singh, and Günter Lepperdinger
+ t0 W, `- h% x1 {- h) r; K/ kEndothelial Progenitor Cells and Nitric Oxide: Matching" t4 U6 ?2 z% E. V4 O7 T- f
Partners in Biomedicine . . . . . . . . . . . . . . . . . . . . . . . . . . . 2133 M8 `: y8 u9 E- H( w
Stefanie Keymel, Burcin Özüyaman, Marijke Grau, Malte Kelm,
q2 H, ]& [( C- uand Petra Kleinbongard
' A: ?+ O& @- l3 M( O! R( F+ fSkeletal Stem Cells and Controlled Nanotopography . . . . . . . . . . . 247% V8 y8 d. e5 f2 L) T
Matthew J. Dalby and Richard O.C. Oreffo0 X. [- H" W9 @1 J G
Part III Clinical Applications
5 j; T( v1 ?% H' RCells and Vascular Tissue Engineering . . . . . . . . . . . . . . . . . . . 261. X5 L8 C; ~) j) B- ?" F0 j2 }! O
John Paul Kirton, Tsung-Neng Tsai, and Qingbo Xu
1 ~: H- J7 p r! f" M: OEndothelial Progenitor Cells for Vascular Repair . . . . . . . . . . . . . 2976 a& O+ q ]* u, U, _3 I# u9 F! ?
Melissa A. Brown, Cindy S. Cheng, and George A. Truskey& b" p9 S4 t0 u y3 Z
Regenerating Tubules for Kidney Repair . . . . . . . . . . . . . . . . . 3216 e5 N4 P4 c( T
W.W. Minuth, L. Denk, and A. Roessger
! L" w* W( i1 Y" i% H, k/ D: HStem Cells in Tissue Engineering and Cell Therapies/ G/ }+ K1 M* @9 J8 ^( {' j9 ~
of Urological Defects . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 345
1 Z( t7 L4 y+ D1 n6 h7 H' G8 i; EChristoph Becker, Katrin Montzka, and Gerhard Jakse+ K" A" b7 A; N' c
Bio-synthetic Encapsulation Systems for Organ Engineering:2 J: [, `( t! I+ p
Focus on Diabetes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 363
% f" n# i J2 o. y: `1 l9 w) T& rRylie A. Green, Penny J. Martens, Robert Nordon,# X6 u8 N6 b% Z$ l9 M% M. V
and Laura A. Poole-Warren
1 k: J9 ?; ^, z9 {0 \ a6 CStem Cell Engineering for Regeneration of Bone Tissue . . . . . . . . . 383
( F; r- g4 m) Y2 y; _! I4 I) pMichael Gelinsky, Anja Lode, Anne Bernhardt, and4 R6 _( |+ A9 K D; D' @
Angela Rösen-Wolff Z4 k: @/ u$ T8 U( @, G; c
Part IV Techniques and Applications
4 z9 X( E* n" I/ S I) v7 _7 @# | ~Building, Preserving, and Applying Extracellular Culture
( m% N0 m) ]" K+ [/ LIntegrity Using New Cell Culture Methods and Surfaces . . . . . . . . . 403" B7 \3 R7 F. }- n; X* N ^7 R2 G
Thomas Brevig, Robin Wesselschmidt, and Masayuki Yamato' b) C2 m) _5 P. K' [' c/ v
Fabrication of Modified Extracellular Matrix
, m% k. B0 r- X8 }* Q0 L4 Qfor the Bone Marrow-Derived Mesenchymal Stem Cell
, u# b8 L1 ^9 {- w' b r8 tTherapeutics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 417) W2 C( L6 T8 B7 X$ W
Hwal (Matthew) Suh
: b1 O' ?; E* h1 {& ]% }6 X9 e" \Neural Stem Cells: From Cell Fate and Metabolic Monitoring
* d. P9 q# E6 H7 ^& g ZToward Clinical Applications . . . . . . . . . . . . . . . . . . . . . . . . 435" F0 h! B: H: }$ ?
Jan Pruszak, Máté Döbrössy, Jochen Kieninger, Kuppusamy* }1 f6 X* N$ }- P0 M4 \8 q/ x
Aravindalochanan, Gerald A. Urban, and Guido Nikkhah4 J3 J2 ]% b8 N5 ^3 S
Contents xxxiii# E2 C& H# z9 w e$ `7 @
Adult Stem Cells in Drug Discovery . . . . . . . . . . . . . . . . . . . . 457. h! P; }+ \& t' J
Stefan Golz, Andreas Geerts, and Andreas Wilmen
0 q. G: l+ [2 ~3 y* k" x* ~, U' s2 K, }Embryonic Stem Cells as a Tool for Drug Screening and Toxicity Testing 473# J+ U: l2 v4 G/ z
Bernd Denecke and Silke Schwengberg1 @) M; S. Z) w, |5 C- R
Embryonic Stem Cells: A Biological Tool to Translate the0 t" T/ O5 l) T5 L
Mechanisms of Heart Development . . . . . . . . . . . . . . . . . . . . 5019 D/ f9 ~. d, e* j0 R, Q) `0 e. ]
Omonigho A. Aisagbonhi and Antonis K. Hatzopoulos
2 W, D; m1 F1 m+ R# bIndex . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 521 |
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