PDF电子书：Stem Cell Engineering Principles and Applications 2011

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Book Title
7 l' t  C# A3 ?! @; ^: T: `  k/ [Stem Cell Engineering
) h, \. D/ M$ TBook Subtitle
8 Q# Q2 t# {+ C7 G9 o# KPrinciples and Applications
% T' C( g! n) WCopyright
. u) D7 p  t% Q1 L20119 Q+ k) _. ^% O! d
DOI( I* ~" A2 {- n0 L
10.1007/978-3-642-11865-44 O7 T4 Q7 f6 `$ k4 {) G
Print ISBN0 L! q+ J+ H3 x# ~, ~" o
978-3-642-11864-7! [6 i! h3 w3 M: U8 n2 U/ D
Online ISBN
+ F2 v' g% Y) q- N  S$ q* u( L+ p! [978-3-642-11865-4
" E: O6 X7 Q: f, F: f) `Publisher
7 {# f( J* }7 F- ]0 J. U: d  s; xSpringer Berlin Heidelberg7 `5 x! A3 i, F4 a5 e* y9 V, Y
Copyright Holder
9 Y- o9 H4 h0 n1 I4 ?- nSpringer-Verlag Berlin Heidelberg
$ q8 W; }5 l- A) B- j! G3 V. ]* ~% k$ \( o3 v/ \9 N) ]
- Reviews Engineering Approaches in Stem Cell Research; Y4 L) X9 M2 i
- Provides a solid reference for researchers and advanced graduate student/ I& e; e: B9 c) U# U
The potential of stem cells for healing and disease prevention in all fields of medicine is tremendous and has revolutionized the high-tech biomedical research. In this book, many of the most prominent researchers discuss the challenging topics of stem cell engineering, for example: Ethical issues of stem cell research; technological challenges, stem cell growth and differentiation, therapeutic applications, bioreactors and bioprocesses, high throughput and microfluidic screening platforms, stem cell identification and sorting, intercellular signaling and engineered niches, novel approaches for embryonic and adult stem cell growth and differentiation, stem cells and drug discovery, screening platforms. Stem Cell Engineering offers valuable background and reference for both the public and professionals including industrial staffers, faculty, researchers, engineers, students and scientific journalists.+ b4 Y" g- K, l  L
Content Level » Research5 ~9 r. r$ }4 ~) H4 x) ~

$ D1 B( b( C- V3 ~2 |  h7 r( pKeywords » bioreactors - cell expansion - differentiation - drug discovery - embryonic stem cell growth - stem cell growth7 d3 N4 Z9 c4 W+ n" o( T
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Related subjects » Biomedical Engineering - Biotechnology - Cell Biology
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$ o' y8 M0 b, UContents
2 y9 [7 c* x2 s( r# f1 M: ?Part I Instead of an Introduction – The Emperor’s New Legs
/ G  a( ^) Y3 u; |$ a. {The Emperor’s New Body: Seeking for a Blueprint of Limb
9 B. m7 P5 l7 Y4 M5 P$ `* ?Regeneration in Humans . . . . . . . . . . . . . . . . . . . . . . . . . . 3
+ T: r: S* v# m8 r; wIlya Digel and Aysegül Temiz Artmann
7 J& N3 [* b! ~$ p% QPart II Basics and Basic Research
7 t: _- s# A& F5 {. EEngineering the Stem Cell Niche and the Differentiative Microand. j; A2 L8 }9 U( {' ^
Macroenvironment: Technologies and Tools for Applying
3 Y" C6 {+ W7 V; YBiochemical, Physical and Structural Stimuli and Their Effects
9 x' {! x& P6 }on Stem Cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41
7 g- a9 e4 y8 x: }% q5 ePaolo Di Nardo, Marilena Minieri, and Arti Ahluwalia
7 l" G% K8 g* t: c& WDifferentiation Potential of Adult Human Mesenchymal Stem Cells . . 61
% f3 c( r- |: ]5 _4 L9 [Edda Tobiasch
. l! [/ L$ b5 r) d: YThe Potential of Selectively Cultured Adult Stem Cells- c/ b: b" p  Z2 N
Re-implanted in Tissues . . . . . . . . . . . . . . . . . . . . . . . . . . . 79
  C, e2 u& d7 OIsgard S. Hueck, Martin Haas, Rita Finones, Jane Frimodig,
* x) X" |0 x6 ?and David A. Gough! y: m# q2 x7 P3 @, c# w# T
Enhanced Cardiac Differentiation of Mouse Embryonic Stem
# T3 `0 a. n6 V: O4 \! S7 XCells by Electrical Stimulation . . . . . . . . . . . . . . . . . . . . . . . 1194 {  ~" B7 t% y; p+ ?6 ?% \, F
Paul R. Bidez III, J. Yasha Kresh, Yen Wei, and Peter I. Lelkes: f2 H1 n+ R" @, y
The Therapeutic Potential of ES-Derived Haematopoietic Cells . . . . . 1439 C& N$ D$ ]; P. t5 t
Sabrina Gordon-Keylock and Lesley Forrester3 v$ x* h( w1 p3 g* i
Genetic Modification of Human Embryonic and Induced+ s- q1 q9 ~4 e$ b, n0 g
Pluripotent Stem Cells: Viral and Non-viral Approaches . . . . . . . . . 159
. j8 @* T3 j% c; w7 [- o$ zNicole M. Kane, Chris Denning, and Andrew H. Baker6 ?8 Y  X4 t- D  ~
The Immune Barriers of Cell Therapy with Allogenic Stem7 h( K" m& ]! d0 r- U
Cells of Embryonic Origin . . . . . . . . . . . . . . . . . . . . . . . . . 181
$ D7 D& z( `( g0 E5 k9 |+ }Olivier Preynat-Seauve, Karl-Heinz Krause, and Jean Villard2 V6 j; H$ n+ L, G* P/ f6 O
xxxi
3 j, W% x9 |* i) O% K  {xxxii Contents2 I' ?; a3 W: U" d
Reponses of Mesenchymal Stem Cells to Varying Oxygen! o1 B+ s7 F* L2 }' n
Availability In Vitro and In Vivo . . . . . . . . . . . . . . . . . . . . . . 199
( l5 P5 c. r' [: e, m& G3 OFrank R. Kloss, Sarvpreet Singh, and Günter Lepperdinger
8 x' a; L, t: h( s" Q- QEndothelial Progenitor Cells and Nitric Oxide: Matching9 o8 d7 h6 Y0 |% ^( ~4 i1 T
Partners in Biomedicine . . . . . . . . . . . . . . . . . . . . . . . . . . . 213
8 W/ {) _& M6 {: @( B" iStefanie Keymel, Burcin Özüyaman, Marijke Grau, Malte Kelm,/ g7 X9 T' A  _6 T
and Petra Kleinbongard
1 D: I: `+ Q3 oSkeletal Stem Cells and Controlled Nanotopography . . . . . . . . . . . 247
: |5 L1 `, T; g3 @  L: ZMatthew J. Dalby and Richard O.C. Oreffo$ ^$ {2 @2 S+ d. L, k( H  n/ p* E- Y
Part III Clinical Applications9 V( z8 f" l* Z( o
Cells and Vascular Tissue Engineering . . . . . . . . . . . . . . . . . . . 261/ b! Q: g0 C4 G4 S# ~* b$ H; Z
John Paul Kirton, Tsung-Neng Tsai, and Qingbo Xu
8 c" F- B  N* FEndothelial Progenitor Cells for Vascular Repair . . . . . . . . . . . . . 297
4 X0 r$ |+ n' |9 oMelissa A. Brown, Cindy S. Cheng, and George A. Truskey
+ T, X8 g1 W% m" E- vRegenerating Tubules for Kidney Repair . . . . . . . . . . . . . . . . . 321
! R2 R- M+ e8 s, _5 r5 z' Y% y2 NW.W. Minuth, L. Denk, and A. Roessger
; O' Z1 C* [- S: ^Stem Cells in Tissue Engineering and Cell Therapies
9 @2 O+ h- y; h6 |of Urological Defects . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 345" p5 I, ^$ e0 }
Christoph Becker, Katrin Montzka, and Gerhard Jakse: U/ [% w4 c" F3 I, Y
Bio-synthetic Encapsulation Systems for Organ Engineering:' b" W4 ]5 s7 Y7 r+ C" Y
Focus on Diabetes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 363
$ S: C- z1 W' fRylie A. Green, Penny J. Martens, Robert Nordon,
: F3 `2 k0 m; w- {and Laura A. Poole-Warren
9 B0 e; q6 h( b4 \  BStem Cell Engineering for Regeneration of Bone Tissue . . . . . . . . . 383) z" W7 z1 l) \& ^/ Q+ k. q" C
Michael Gelinsky, Anja Lode, Anne Bernhardt, and
8 O4 |. r" r8 k( @Angela Rösen-Wolff7 p# w" B0 B! {* q+ q
Part IV Techniques and Applications  X& d" [1 J) v8 c
Building, Preserving, and Applying Extracellular Culture
6 G# J2 L) q3 `9 ]$ `Integrity Using New Cell Culture Methods and Surfaces . . . . . . . . . 403' Q) t- U+ |) v- _: m8 g
Thomas Brevig, Robin Wesselschmidt, and Masayuki Yamato
: L/ d3 U0 j3 O; [Fabrication of Modified Extracellular Matrix# c" H2 {+ N7 w# ^, `3 x% T" _8 W) i
for the Bone Marrow-Derived Mesenchymal Stem Cell. Y# E% [6 ^" O) J7 [/ m
Therapeutics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 417& h  t. t& `# E( l  f- H5 D$ K
Hwal (Matthew) Suh' c& H* x+ F7 K4 |/ ~
Neural Stem Cells: From Cell Fate and Metabolic Monitoring
& m' }+ o, Q# q" E) V6 ~6 OToward Clinical Applications . . . . . . . . . . . . . . . . . . . . . . . . 435
: i8 T3 a; A1 N! _/ c! ^4 `Jan Pruszak, Máté Döbrössy, Jochen Kieninger, Kuppusamy! n1 v$ h/ i. ?: E  R
Aravindalochanan, Gerald A. Urban, and Guido Nikkhah( w- k3 {* k2 x( [; {1 }0 |" n
Contents xxxiii
# _: N2 u9 Z3 T! @Adult Stem Cells in Drug Discovery . . . . . . . . . . . . . . . . . . . . 457
; B3 r. f" E' t5 AStefan Golz, Andreas Geerts, and Andreas Wilmen
+ {, x' z1 \* }Embryonic Stem Cells as a Tool for Drug Screening and Toxicity Testing 473/ K5 H# |; x5 G# @
Bernd Denecke and Silke Schwengberg
1 q7 m; I5 B& X: M% G" OEmbryonic Stem Cells: A Biological Tool to Translate the8 B" O) m8 D+ U  z- J/ K) }
Mechanisms of Heart Development . . . . . . . . . . . . . . . . . . . . 501
8 w% E4 H6 t$ i; G) Q3 n8 YOmonigho A. Aisagbonhi and Antonis K. Hatzopoulos. X# Q+ x" R3 y( _! m& v
Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 521

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nichifanlema2

谢谢

暖羊羊

非常感谢

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