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本帖最后由 细胞海洋 于 2013-2-21 10:11 编辑
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' g3 k9 \* v4 uBook Title
6 v( V. m. i7 T& A) ]) j {* m: IStem Cell Engineering
3 K( Y0 t1 l* ~: WBook Subtitle
6 Q9 A& C0 L6 ]# PPrinciples and Applications
! G1 K. i% y3 ICopyright0 q2 U( t4 B) v& W' F$ L
2011* {$ M8 z7 w* ~1 N1 c) v
DOI
* L/ F3 s. ~- C1 B10.1007/978-3-642-11865-4
3 [4 ?; E8 P& l" \ zPrint ISBN4 A i* v3 X+ |) `: k
978-3-642-11864-7
- D) g1 h' b6 C4 y2 |Online ISBN0 Q& g/ Q" H7 M# G, s. G2 b
978-3-642-11865-4# m9 H; n! h% E5 }2 H1 I' d) ~
Publisher7 u/ x" ~, ?, P: n3 B, |2 F* Y
Springer Berlin Heidelberg
' ~7 b) ]% c2 y+ W* h- y( y' {7 CCopyright Holder
. V) x: X: T# k5 v4 eSpringer-Verlag Berlin Heidelberg2 q5 ?, v) S1 C4 ~' V/ D
{% a# ? y: N2 }- {9 j- Reviews Engineering Approaches in Stem Cell Research: x6 R7 S0 M0 W8 `9 E1 E- b. W
- Provides a solid reference for researchers and advanced graduate student
" W9 F, a V6 `9 wThe potential of stem cells for healing and disease prevention in all fields of medicine is tremendous and has revolutionized the high-tech biomedical research. In this book, many of the most prominent researchers discuss the challenging topics of stem cell engineering, for example: Ethical issues of stem cell research; technological challenges, stem cell growth and differentiation, therapeutic applications, bioreactors and bioprocesses, high throughput and microfluidic screening platforms, stem cell identification and sorting, intercellular signaling and engineered niches, novel approaches for embryonic and adult stem cell growth and differentiation, stem cells and drug discovery, screening platforms. Stem Cell Engineering offers valuable background and reference for both the public and professionals including industrial staffers, faculty, researchers, engineers, students and scientific journalists.
: R% h3 J/ j3 _* eContent Level » Research' M* i: q2 h: m6 x$ z7 d1 ]+ L
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Keywords » bioreactors - cell expansion - differentiation - drug discovery - embryonic stem cell growth - stem cell growth' o- K* J* l! n
9 p1 H3 c2 R( zRelated subjects » Biomedical Engineering - Biotechnology - Cell Biology
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Contents8 j7 i! F. C4 Z) k8 l2 M
Part I Instead of an Introduction – The Emperor’s New Legs( w9 m7 u& ]2 M/ ] `
The Emperor’s New Body: Seeking for a Blueprint of Limb
4 ^2 z# J( a- `) V+ qRegeneration in Humans . . . . . . . . . . . . . . . . . . . . . . . . . . 3
0 x) v7 y% z$ e, q6 T4 [, B& i2 TIlya Digel and Aysegül Temiz Artmann
; z S# p# n* @) M. }Part II Basics and Basic Research) d4 u: Z" e2 ^! A5 }
Engineering the Stem Cell Niche and the Differentiative Microand
+ P' N8 [7 p9 `3 O. N& V( a( _Macroenvironment: Technologies and Tools for Applying i! a; c. @; @4 [3 Q
Biochemical, Physical and Structural Stimuli and Their Effects
; m3 n3 K! `4 m( z3 Mon Stem Cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41
6 O; i3 c" A1 w `& wPaolo Di Nardo, Marilena Minieri, and Arti Ahluwalia
7 S" k) K: ]+ e, \( k& ^0 D9 m4 B: cDifferentiation Potential of Adult Human Mesenchymal Stem Cells . . 61* V# s1 l9 E: S' U) a
Edda Tobiasch% L f( E- c: _4 U* T0 o
The Potential of Selectively Cultured Adult Stem Cells
: w- f5 q) z$ E7 E4 tRe-implanted in Tissues . . . . . . . . . . . . . . . . . . . . . . . . . . . 79
1 V( b+ E( c9 T+ k+ b7 tIsgard S. Hueck, Martin Haas, Rita Finones, Jane Frimodig,
9 W# v% c8 B, }' O3 R2 pand David A. Gough' @8 G( ~+ R' A" l& u1 [) S0 T
Enhanced Cardiac Differentiation of Mouse Embryonic Stem' |& Z% D$ q1 R" G
Cells by Electrical Stimulation . . . . . . . . . . . . . . . . . . . . . . . 119$ Q4 b9 O$ l( y, m6 g
Paul R. Bidez III, J. Yasha Kresh, Yen Wei, and Peter I. Lelkes/ t1 l! m1 e( v( Q/ ^: j& u6 s! M
The Therapeutic Potential of ES-Derived Haematopoietic Cells . . . . . 143
8 X5 F: \2 Z+ [, J2 mSabrina Gordon-Keylock and Lesley Forrester
: X2 K' R( O( T" B3 ]8 YGenetic Modification of Human Embryonic and Induced
! W% s3 J/ @& b6 o2 P$ q1 zPluripotent Stem Cells: Viral and Non-viral Approaches . . . . . . . . . 159
0 F i( u3 `/ V5 {; uNicole M. Kane, Chris Denning, and Andrew H. Baker
}7 Z; A5 |, e( ~; yThe Immune Barriers of Cell Therapy with Allogenic Stem/ c: J& i, _7 U0 g7 _$ V
Cells of Embryonic Origin . . . . . . . . . . . . . . . . . . . . . . . . . 181- E C# m- Y5 K7 C
Olivier Preynat-Seauve, Karl-Heinz Krause, and Jean Villard
0 X' n0 `2 q# Z1 \0 Ixxxi
* u6 r2 ]5 F3 ?8 f; C; w6 O3 V! U$ Cxxxii Contents
% S5 @' Y/ n- K1 M- @# N' n8 P2 e8 AReponses of Mesenchymal Stem Cells to Varying Oxygen2 n- L- R2 l& H H+ j* x
Availability In Vitro and In Vivo . . . . . . . . . . . . . . . . . . . . . . 199
# N! ?9 O( _2 j6 _' V& LFrank R. Kloss, Sarvpreet Singh, and Günter Lepperdinger7 ^+ m, v9 w3 x/ D% E! Z3 |
Endothelial Progenitor Cells and Nitric Oxide: Matching
2 P8 o8 c# R+ Z3 ]5 m1 j) ` bPartners in Biomedicine . . . . . . . . . . . . . . . . . . . . . . . . . . . 213
/ \/ C8 Z z: V, P. iStefanie Keymel, Burcin Özüyaman, Marijke Grau, Malte Kelm, K+ Y6 ?6 I+ d+ M$ `
and Petra Kleinbongard+ j3 P& d% [7 F8 V$ L
Skeletal Stem Cells and Controlled Nanotopography . . . . . . . . . . . 247, @9 R) ~5 T* l/ E8 d$ m6 P
Matthew J. Dalby and Richard O.C. Oreffo& u z, p- C* `! r( u- y8 ?
Part III Clinical Applications8 S$ _0 R5 _% \: ~
Cells and Vascular Tissue Engineering . . . . . . . . . . . . . . . . . . . 261
3 }1 `1 C' G2 e$ d \ cJohn Paul Kirton, Tsung-Neng Tsai, and Qingbo Xu. ~& [* B: R. k, e6 Q
Endothelial Progenitor Cells for Vascular Repair . . . . . . . . . . . . . 297
3 B3 \4 z- @9 P, j) NMelissa A. Brown, Cindy S. Cheng, and George A. Truskey
3 f, r3 w8 K* E# S9 w% i( @Regenerating Tubules for Kidney Repair . . . . . . . . . . . . . . . . . 321
: A) M! a# t" `& zW.W. Minuth, L. Denk, and A. Roessger
4 U4 g8 A& i3 `) _+ Q& F5 bStem Cells in Tissue Engineering and Cell Therapies6 u* y* |! S/ }. o" p5 i& W
of Urological Defects . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 345
5 i6 Q7 q' f9 H. h+ k8 MChristoph Becker, Katrin Montzka, and Gerhard Jakse7 U; _* V$ t) K |$ b
Bio-synthetic Encapsulation Systems for Organ Engineering:
+ R: _5 z2 G! `5 hFocus on Diabetes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 363
& s/ y) t5 C4 h8 v% d cRylie A. Green, Penny J. Martens, Robert Nordon,
% x c. D1 t; C( `7 aand Laura A. Poole-Warren
8 M7 d+ L. `6 U* c3 P1 q5 l% IStem Cell Engineering for Regeneration of Bone Tissue . . . . . . . . . 383
7 n9 w' n/ [: i: L0 H4 IMichael Gelinsky, Anja Lode, Anne Bernhardt, and; m. v# ^( x7 ~# {! Q% P7 ~% `
Angela Rösen-Wolff
7 a# D. j" q* J1 p: J2 z6 @Part IV Techniques and Applications
6 r) T& o/ D' y& A. PBuilding, Preserving, and Applying Extracellular Culture
0 {- a3 Y" B! _1 X- mIntegrity Using New Cell Culture Methods and Surfaces . . . . . . . . . 403
" w* w3 a b9 l) ^Thomas Brevig, Robin Wesselschmidt, and Masayuki Yamato7 g, p. W' A2 a, l/ S) y% m
Fabrication of Modified Extracellular Matrix
+ U' a8 y9 |6 G* `0 m1 M3 xfor the Bone Marrow-Derived Mesenchymal Stem Cell) h9 C* B7 ]8 S
Therapeutics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 417
/ x4 j. p. S mHwal (Matthew) Suh2 m/ `$ p4 U1 u, |! K" \2 ]# o( y
Neural Stem Cells: From Cell Fate and Metabolic Monitoring
6 h( j/ C1 E2 {- SToward Clinical Applications . . . . . . . . . . . . . . . . . . . . . . . . 435
; h8 M3 ]7 q4 J, aJan Pruszak, Máté Döbrössy, Jochen Kieninger, Kuppusamy
( E( ]: X2 X+ J' `% z" M! A3 |Aravindalochanan, Gerald A. Urban, and Guido Nikkhah1 W: o& u2 j+ f3 z
Contents xxxiii2 t* |* R& l0 |1 z3 ?4 l
Adult Stem Cells in Drug Discovery . . . . . . . . . . . . . . . . . . . . 457$ |, L( ^# Z. E9 E" P
Stefan Golz, Andreas Geerts, and Andreas Wilmen
3 F9 y- A+ T, d' x+ W$ bEmbryonic Stem Cells as a Tool for Drug Screening and Toxicity Testing 473
& O/ F; |* k& Y/ e. x" rBernd Denecke and Silke Schwengberg
! W; G! A3 e, [6 u/ k* KEmbryonic Stem Cells: A Biological Tool to Translate the5 q0 ]# L2 `" `* F: {
Mechanisms of Heart Development . . . . . . . . . . . . . . . . . . . . 501
8 p6 K; Q# q, g# q$ {Omonigho A. Aisagbonhi and Antonis K. Hatzopoulos9 d0 b. P2 x" f$ X: m2 ?: s
Index . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 521 |
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