求Nature Genetics文献一篇，谢谢

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Nat Genet. 2013 Mar;45(3):239-41. doi: 10.1038/ng.2530. Epub 2013 Jan 20.
/ {7 e! X8 j6 o8 g# Z' OXACT, a long noncoding transcript coating the active X chromosome in human pluripotent cells.
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Source
  Z& x; Y: @. d1] Université Paris Diderot, Sorbonne Paris Cité, Epigenetics and Cell Fate, Paris, France. [2] Centre National de la Recherche Scientifique (CNRS), Unité Mixte de Recherche (UMR) 7216 Epigenetics and Cell Fate, Paris, France.
; D6 }4 L' m9 B! r$ |1 pAbstract
& P* m6 [9 s" t% ^/ B3 `; J# CX-chromosome inactivation (XCI) in mammals relies on XIST, a long noncoding transcript that coats and silences the X chromosome in cis. Here we report the discovery of a long noncoding RNA, XACT, that is expressed from and coats the active X chromosome specifically in human pluripotent cells. In the absence of XIST, XACT is expressed from both X chromosomes in humans but not in mice, suggesting a unique role for XACT in the control of human XCI initiation.  e9 D( W, r, b, v/ d( c
http://www.nature.com/ng/journal/v45/n3/full/ng.2530.html' O1 `6 W7 r$ j" t1 ^1 j, Z

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