求Nature Genetics文献一篇，谢谢

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2 A, H! W  Q5 ~Nat Genet. 2013 Mar;45(3):239-41. doi: 10.1038/ng.2530. Epub 2013 Jan 20.
6 K1 z- E. G8 ], zXACT, a long noncoding transcript coating the active X chromosome in human pluripotent cells.
8 C- K% f4 z$ c4 S( s3 e- @: ?8 ^Vallot C, Huret C, Lesecque Y, Resch A, Oudrhiri N, Bennaceur-Griscelli A, Duret L, Rougeulle C.* `" s; H& U% K1 F: ^8 F
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1] Université Paris Diderot, Sorbonne Paris Cité, Epigenetics and Cell Fate, Paris, France. [2] Centre National de la Recherche Scientifique (CNRS), Unité Mixte de Recherche (UMR) 7216 Epigenetics and Cell Fate, Paris, France.& a% _& T1 p. ^
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X-chromosome inactivation (XCI) in mammals relies on XIST, a long noncoding transcript that coats and silences the X chromosome in cis. Here we report the discovery of a long noncoding RNA, XACT, that is expressed from and coats the active X chromosome specifically in human pluripotent cells. In the absence of XIST, XACT is expressed from both X chromosomes in humans but not in mice, suggesting a unique role for XACT in the control of human XCI initiation.
# a: N; s$ X& A2 vhttp://www.nature.com/ng/journal/v45/n3/full/ng.2530.html
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