PDF电子书：Embryonic Stem Cells – Differentiation and Pluripotent Alternatives

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5 L) R3 A" x( b; L( [9 D( _' hEmbryonic Stem Cells – Differentiation and Pluripotent Alternatives4 \2 O: @- ], g, M' T* [0 d% }
Edited by Michael S. Kallos
# P5 P8 `) d& B* o% u  dPublished by InTech
1 T8 X# Z" @$ z+ o% i' @0 r6 `' J: |Janeza Trdine 9, 51000 Rijeka, Croatia
( t( r; G3 J+ r3 g/ `8 W6 z# T2 pCopyright © 2011 InTech6 {8 X1 P0 d3 F; w) _, K
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Contents
! i2 \' ?: j; F3 `Preface IX$ C+ j$ M  P. X" A) [1 O1 l
Part 1 General Differentiation 1
  E. E/ g9 D& y/ S" s6 m7 WChapter 1 Role of Signaling Pathways and Epigenetic0 E7 I, k7 b( Z
Factors in Lineage Determination During
2 t0 A* e3 i6 |: q, e5 SHuman Embryonic Stem Cell Differentiation 3
1 o2 Q  x3 N8 }' U3 `8 }Prasenjit Sarkar and Balaji M. Rao/ d4 r3 l8 H: x8 f/ P/ l
Chapter 2 Bioactive Lipids in Stem Cell Differentiation 338 w( N4 u5 A5 H+ U. _
Erhard Bieberich and Guanghu Wang
; H/ c; _; {1 H# A+ ^Chapter 3 Retinoid Signaling is a Context-Dependent/ V2 f  w4 ?; a: D. p2 y
Regulator of Embryonic Stem Cells 55& e6 U9 L8 K9 q& R0 ?* Y
Zoltan Simandi and Laszlo Nagy
: R! E$ H" z) jPart 2 Neural and Retinal Differentiation 79, ?: ?# t$ A: i. }6 S& V0 r# e$ \
Chapter 4 Pluripotent Stem Cells as an In Vitro
/ u% z, ?1 u; j8 C- yModel of Neuronal Differentiation 81/ C  S+ A0 o% _5 q
Irina Kerkis, Mirian A. F. Hayashi,
- S  g6 ^  _1 r$ nNelson F. Lizier, Antonio C. Cassola,
; s, l7 ?( C: cLygia V. Pereira and Alexandre Kerkis
; v' m4 d0 t6 `9 v8 `1 sChapter 5 Characterization of Embryonic Stem (ES)
2 `9 c, j3 @# t: C# a- cNeuronal Differentiation Combining Atomic Force,# `+ D5 M1 Q! Q5 A& V
Confocal and DIC Microscopy Imaging 99" v( m4 `2 H8 H2 [* W0 {
Maria Elisabetta Ruaro, Jelena Ban and Vincent Torre
% i' Y2 G: f; u2 a* W" Q+ `5 M4 HChapter 6 Oligodendrocyte Fate Determination. w" G7 N, C- Y# B2 J# Y* B
in Human Embryonic Stem Cells 119$ q0 ?# `! {" @3 o- K7 Z
Siddharth Gupta, Angelo All and Candace Kerr
* w) T9 e# |: a& U: SChapter 7 Stem-Cell Therapy for Retinal Diseases 135
$ f" T- }1 i" i2 y% n& cRubens Camargo Siqueira
' U% ?* O5 e/ I! c& y" EVI Contents9 t5 q. K; N/ g: k. d
Part 3 Cardiac and Other Myogenic Differentiation 149
( S+ c: t& V. @, }( Y. _8 N, `Chapter 8 Transcriptional Networks' S/ \( L7 ~6 ]" X# {; u
of Embryonic Stem Cell-Derived Cardiomyogenesis 151
7 O5 E' x- M2 m" H, jDiego Franco, Estefania Lozano-Velasco and Amelia Aránega6 ^* ?' Y( E! s: A: v- z
Chapter 9 Human Pluripotent Stem Cells3 p3 j; s% U) a9 {/ n# E% X" b3 N
in Cardiovascular Research and Regenerative Medicine 169
3 P7 G6 L! b5 BEllen Poon, Chi-wing Kong and Ronald A. Li
* f9 T8 V0 e* p; F/ xChapter 10 Human Pluripotent Stem Cell-Derived Cardiomyocytes:7 O! q. O6 S% J+ x; x
Maturity and Electrophysiology 185! _& f( v% b" m
Ville Kujala, Mari Pekkanen-Mattila and Katriina Aalto-Setälä: c2 r& \9 Z5 ]% M/ ]$ e
Chapter 11 Maintenance Of Calcium Homeostasis/ c- Z: e' v# |% ~
in Embryonic Stem Cell-Derived Cardiomyocytes 205" P& c$ D3 P9 g5 W
Iek Chi Lo, Chun Kit Wong and Suk Ying Tsang
4 i$ |& l& j, ~% ?Chapter 12 Myogenic Differentiation of ES Cells for Therapies
1 N( ^+ [" J9 @8 N( h* w1 e) ]- s6 Ein Neuromuscular Diseases: Progress to Date 227
8 ]# `3 A+ a1 n' xCamila F. Almeida, Danielle Ayub-Guerrieri and Mariz Vainzof
0 F3 p  V( H4 B: i6 DPart 4 Endothelial Differentiation 243) J6 ]3 }" }% i
Chapter 13 Dissecting the Signal Transduction Pathway" r. B$ m7 O" ^1 N: t: f( ]
that Directs Endothelial Differentiation Using
) H; P8 A. j1 yEmbryonic Stem CellDerived Vascular Progenitor Cells 245
$ b: o+ G' ~/ w$ V% }Kyoko Kawasaki and Keiji Miyazawa& H7 ^" l, l& ?% D
Chapter 14 Endothelial Differentiation of Embryonic Stem Cells 267
9 R; j* W3 I1 V: b; ?4 ?2 vPeter Oettgen
9 u6 c- p, b* N# H. ^' N  @1 F+ q; APart 5 Hepatic Differentiation 277
+ w5 V1 U) x1 `4 {) U) nChapter 15 Stem Cells for HUMAN Hepatic Tissue Engineering 279
0 \9 m' o$ B- u! i' a, n* zN.I. Nativ, M.A. Ghodbane, T.J. Maguire,& i' j8 @# h5 {$ i) n
F. Berthiaume and M.L. Yarmush
7 I* x3 E! G9 W+ T( _8 L: dChapter 16 Hepatic Differentiation of Human Embryonic and Induced
2 [( a3 C6 n' V( A* v" n, TPluripotent Stem Cells for Regenerative Medicine 303
; I5 e5 d0 Z0 g! tToshio Miki' T$ L$ C* W! ?/ ~  \! I
Part 6 Osteogenic Differentiation 321
8 O' w! h$ h" e; o* I$ PChapter 17 Osteogenesis from Pluripotent Stem Cells:
$ Z" @# w* d- dNeural Crest or Mesodermal Origin? 323& J1 G, H" ]- f/ \" G% v& ^
Kevin C. Keller and Nicole I. zur Nieden9 }" V# N$ T( C* g8 H: q
Contents VII
4 F2 y3 b+ Z# LPart 7 Pluripotent Alternatives –
* J, q# U- Z$ B3 B9 V2 l) JInduced Pluripotent Stem Cells (iPSCs) 349
4 O' e- |* l4 z( E3 }: Y2 }$ h+ lChapter 18 The Past, Present and Future of
6 C2 i" V4 E# u4 S( U8 g( H- EInduced Pluripotent Stem Cells 351
; ]3 S- l8 ?9 X" k* \Koji Tanabe and Kazutoshi Takahashi
: K+ ]  u  f2 J2 ]Chapter 19 New Techniques in the Generation( r5 u) T, W! r: B
of Induced Pluripotent Stem Cells 373
  J8 n, D, `) D* W  tRaymond C.B. Wong, Ellen L. Smith and Peter J. Donovan
* t0 Y2 b) V& E* y8 w& F  }Chapter 20 Generation of ICM-Type Human iPS Cells
7 \) ~  p! J) w/ j# O6 ufrom CD34+ Cord Blood Cells 399# e6 Z9 O3 r- O
Naoki Nishishita, Noemi Fusaki and Shin Kawamata* ^, Z( n* J. J8 Z5 _; m6 Q
Chapter 21 Modelling of Neurological Diseases  v- @! a1 u3 J6 _; T# |# B/ t
Using Induced Pluripotent Stem Cells 413
4 r% K0 Y. a; _' v* C9 mOz Pomp, Chen Sok Lam, Hui Theng Gan,
7 B, i8 ?: M) _" K& \% `- K: lSrinivas Ramasamy and Sohail Ahmed5 _# a% ^; D4 _0 |! l7 L: ^$ N
Part 8 Pluripotent Alternatives - Other Cell Sources 431  L! {! J! c9 C7 i
Chapter 22 Very Small Embryonic/Epiblast-Like Stem Cells (VSELs)
' n- m2 g0 h$ a8 jResiding in Adult Tissues and Their Role. B9 Y# E2 V: L* c4 I  L  V2 _- m
in Tissue Rejuvenation and Regeneration 433  K  [0 m& E$ N
Dong-Myung Shin, Janina Ratajczak,
# C) r' ~5 J% \' ~( x5 ]% ZMagda Kucia and Mariusz Z. Ratajczak3 g1 }1 F# Y- w* q
Chapter 23 Multipotent Dental Stem Cells:
# l$ o8 f3 X; ^, r0 T) vAn Alternative Adult Derived Stem# X7 E* o; M: [& y1 w; e8 o  L
Cell Source for Regenerative Medicine 451
0 F  h) T( O1 N( J7 o) m8 r; X( k  _1 `Tammy Laberge and Herman S. Cheung
, ?9 e8 N) b/ ?- ~( JChapter 24 Pluripotent Stem Cells from Testis 473
1 u4 W9 T- q( ~' O( _4 l9 xSandeep Goel and Hiroshi Imai' |) s/ u% Q( b' e$ D; d
Chapter 25 Amniotic Fluid Stem Cells 493
1 l% W) _' z! a, f) O' O# N) LGianni Carraro, Orquidea H. Garcia,
+ @/ ]" s+ K" c# l) h( l. B' d% f% S3 ]Laura Perin, Roger De Filippo and David Warburton, G  v2 o8 H: n
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