澳大利亚科学家建立了iPS安全性检测方法

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原文出处：http://www.abc.net.au/news/2013-06-04/stem-cell-research/4732158# Q8 U! {! R" P* }

+ q: r6 X; ~, a7 yAustralian scientists have created a test to work out whether certain types of stem cells are unsafe.
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The CSIRO has spent five years developing a safety test for induced pluripotent (iPS) stem cells.
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& H; C) c9 P0 q0 I0 biPS stem cells do not require a human embryo and are considered an important research advance.- ^" S; {4 _* C% F' H* \+ J1 S

$ Z' v1 q- p  ^; Z& BLast month, scientists were able to use human skin cells to create early-stage embryos.
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There is much debate in the scientific community about the advantages of iPS stem cells over their embryonic counterparts.' n. Q: }+ m- a: o( B) {
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The CSIRO's Andrew Laslett says there is still a number of question marks about the long term stability and safety of iPS cells.: D  v$ j% s! S9 ]
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"At this stage it appears that human embryonic stem cells may be slightly safer, but it's early days," he said.8 u/ K- j, U5 ~6 ?" R5 |! A% ?

0 J- K& \6 K& [. }+ ^8 I& S1 x& KDr Laslett says the new test will provide more information about the quality of iPS and help identify unwanted cells that can mutate.
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"Sometimes the cells that are made from the iPS cells change back into stem cells which are unwanted because these cells can form tumours called teratomas," he said.
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Dr Laslett is hoping the research will be used to ensure stem cell therapies are safe for humans.
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2 k) p' @* t4 s! ?) Q6 z"Any cell line that's going to be used for cell therapy has to go through a whole barrage of different tests to see whether they're safe," he said.  K4 w9 |$ K  T
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"We hope that this one will be added to that number of tests... and it's really the first one that's entirely specific for human induced pluripotent stem cells."- I! K5 P1 ]/ F# P9 ?* |2 J; f

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