澳大利亚科学家建立了iPS安全性检测方法

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原文出处：http://www.abc.net.au/news/2013-06-04/stem-cell-research/4732158
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/ p, Y. p# u0 r' p+ B* c" sAustralian scientists have created a test to work out whether certain types of stem cells are unsafe." L2 w" r: U: J2 q4 b
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The CSIRO has spent five years developing a safety test for induced pluripotent (iPS) stem cells.
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iPS stem cells do not require a human embryo and are considered an important research advance.( J3 V0 h% a8 T9 _
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Last month, scientists were able to use human skin cells to create early-stage embryos., M/ y; W! p$ n: x1 o
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There is much debate in the scientific community about the advantages of iPS stem cells over their embryonic counterparts.
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The CSIRO's Andrew Laslett says there is still a number of question marks about the long term stability and safety of iPS cells.
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; t1 c5 U6 X: U* t3 c* z"At this stage it appears that human embryonic stem cells may be slightly safer, but it's early days," he said.
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; d3 y# Z: f3 [9 q5 dDr Laslett says the new test will provide more information about the quality of iPS and help identify unwanted cells that can mutate.$ v6 R" y3 _! c
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"Sometimes the cells that are made from the iPS cells change back into stem cells which are unwanted because these cells can form tumours called teratomas," he said.
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Dr Laslett is hoping the research will be used to ensure stem cell therapies are safe for humans.
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"Any cell line that's going to be used for cell therapy has to go through a whole barrage of different tests to see whether they're safe," he said.) Q+ W4 z+ b6 H: o
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"We hope that this one will be added to that number of tests... and it's really the first one that's entirely specific for human induced pluripotent stem cells."
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