澳大利亚科学家建立了iPS安全性检测方法

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原文出处：http://www.abc.net.au/news/2013-06-04/stem-cell-research/4732158+ @: a* `6 K; M2 O  a' G

8 _2 A0 z) _( h" H$ pAustralian scientists have created a test to work out whether certain types of stem cells are unsafe.
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The CSIRO has spent five years developing a safety test for induced pluripotent (iPS) stem cells.
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! d0 P: D/ s6 E- e" e  Y9 W' miPS stem cells do not require a human embryo and are considered an important research advance.$ q: x' Q, t& W0 F3 G0 X' `  D, H
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Last month, scientists were able to use human skin cells to create early-stage embryos.2 {3 O/ h; M- i1 Q/ T
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There is much debate in the scientific community about the advantages of iPS stem cells over their embryonic counterparts., |( x: A0 K+ M7 R# m& o1 e$ ^
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The CSIRO's Andrew Laslett says there is still a number of question marks about the long term stability and safety of iPS cells.8 {+ t+ P, D( u2 l/ D

& _6 M% w8 X! Y"At this stage it appears that human embryonic stem cells may be slightly safer, but it's early days," he said.
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Dr Laslett says the new test will provide more information about the quality of iPS and help identify unwanted cells that can mutate.1 }4 |$ Z4 {" J* f

1 j" t4 Z2 R1 R1 K& x"Sometimes the cells that are made from the iPS cells change back into stem cells which are unwanted because these cells can form tumours called teratomas," he said.
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! ^4 n  ?. E4 R3 d" ?% c& r+ LDr Laslett is hoping the research will be used to ensure stem cell therapies are safe for humans.+ _' c0 N- y& g- {7 f4 J$ W* x

/ M9 N# `0 ^0 P" I+ I& U6 R& L"Any cell line that's going to be used for cell therapy has to go through a whole barrage of different tests to see whether they're safe," he said.
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9 _7 R& z& T" V% X, w) B: i"We hope that this one will be added to that number of tests... and it's really the first one that's entirely specific for human induced pluripotent stem cells."
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