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9 X; Z6 c8 a ~' \% Y T' U! bCOVER Intestinal organoids (red) derived in vitro from single
" ]( O0 m; l3 u5 I# T" D' Hintestinal stem cells display cryptlike structures with stem and Paneth cells * ?" }7 m- U/ K) x! b0 L
(stem cells, green). Infused mini-guts fill in the ulcerated area of an inflamed
$ N& Z: Y+ B$ K1 X/ C3 Ecolon. Reviews in this special issue on morphogenesis describe recent mini-gut
) c6 W+ Q9 I! f- Z5 _1 f& }technology, as well as advances in light dynamics during development. See the
0 t- n0 @; C1 K& n0 |2 P0 Hspecial section on page 1183 and at
' c9 q+ M# }# P. S# Z7 j* Bwww.sciencemag.org/special/morph.
4 f2 O W) y- w2 XImage: Hans Clevers, Hubrecht Institute
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