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COVER Intestinal organoids (red) derived in vitro from single
7 f# s4 j& q1 o) f+ e/ _; k8 Rintestinal stem cells display cryptlike structures with stem and Paneth cells & o) z/ z. ?1 x% D: P4 F' G
(stem cells, green). Infused mini-guts fill in the ulcerated area of an inflamed
$ R* F% V+ Z2 r9 K8 W; B1 n5 Hcolon. Reviews in this special issue on morphogenesis describe recent mini-gut
( l/ J1 r& L" O) e4 H, \technology, as well as advances in light dynamics during development. See the 8 W. x; \# U4 Q. [
special section on page 1183 and at ' L7 r% [# [8 N7 u" c1 Q' r
www.sciencemag.org/special/morph. 3 _# x0 t- B2 V! E
Image: Hans Clevers, Hubrecht Institute
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