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* o. a7 A" h$ z* D2 }; }COVER Intestinal organoids (red) derived in vitro from single + e: j/ [: | n9 z" W2 P
intestinal stem cells display cryptlike structures with stem and Paneth cells
- T/ }* B" w5 F4 d/ T/ m6 ](stem cells, green). Infused mini-guts fill in the ulcerated area of an inflamed Q0 s& D! |0 l5 L; X1 i
colon. Reviews in this special issue on morphogenesis describe recent mini-gut / I% v4 H4 \) v' ~9 }/ K; R" r. F
technology, as well as advances in light dynamics during development. See the 4 L- }' @* t% u* U
special section on page 1183 and at
) g+ w9 a+ E4 zwww.sciencemag.org/special/morph. % b! U! q$ W5 O$ s, ^
Image: Hans Clevers, Hubrecht Institute ; v# E9 G$ r. |' V9 i' X
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