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& c! k/ g3 ~/ H7 I4 Q+ HCOVER Intestinal organoids (red) derived in vitro from single
* z- Z0 L( O5 ?6 y' S* a" zintestinal stem cells display cryptlike structures with stem and Paneth cells
+ i/ W" D/ C3 U# u( N5 B; q: X(stem cells, green). Infused mini-guts fill in the ulcerated area of an inflamed 5 J9 n0 d/ C3 F8 p" Q M
colon. Reviews in this special issue on morphogenesis describe recent mini-gut
6 D; ]. t8 j2 v4 k+ Ntechnology, as well as advances in light dynamics during development. See the
: O6 P' e& |/ ]3 u5 z' o( bspecial section on page 1183 and at % W+ E+ C* f2 o4 I' v; }5 t8 x
www.sciencemag.org/special/morph. 0 j& O8 _- L6 l
Image: Hans Clevers, Hubrecht Institute 1 h& k/ d! r) k2 Q, M
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