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% n1 U: S, ?7 r0 X0 u3 \2 W& yCOVER Intestinal organoids (red) derived in vitro from single
. w1 d7 X9 a, c3 D% o" Y! }, xintestinal stem cells display cryptlike structures with stem and Paneth cells 6 a: x% r% j; B- Y% M6 X" @& l
(stem cells, green). Infused mini-guts fill in the ulcerated area of an inflamed 7 t3 |0 M& {% s
colon. Reviews in this special issue on morphogenesis describe recent mini-gut
( s/ `3 H- u* F. D0 X* [* m9 Ztechnology, as well as advances in light dynamics during development. See the
4 y) F) x; |, r @special section on page 1183 and at 2 H7 F- q: A$ I! }7 w
www.sciencemag.org/special/morph.
5 D5 a% H8 Q9 b% B0 b/ b4 |Image: Hans Clevers, Hubrecht Institute
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