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- 积分
- 17983
- 威望
- 17983
- 包包
- 26159
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6 J/ ~4 y9 c% P
Toxoplasma gondii infects the mouse gut and induces
+ W3 N9 h; O' J( ]2 v' A3 Zan inflammatory response mediated by neutrophils that damages the intestinal
& F5 t+ Q, ?+ q, I# A8 jtissue and leads to proliferation and translocation of commensal bacteria. In
9 C. j( v$ H5 r! {this issue, Grainger et al. report that commensal bacteria help temper ) j3 `* r: c! B" ]
the inflammation caused by T. gondii by stimulating inflammatory . s* u" e# n& v
monocytes to release prostaglandin E2, which dampens neutrophil activity. The
2 R4 }; Y: R! d) _6 lcover depicts commensal bacteria in blue and intestinal villi in red in mice - A4 z$ X) h, G% k5 n8 E1 h
infected with T. gondii. Image credit: Lily Y. Koo and Michael J. Molloy. " [- @3 a7 S0 a7 m! x _; z
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