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, ?, b5 G- Y. ?Toxoplasma gondii infects the mouse gut and induces # m9 m9 ^& x) T4 L% b0 _5 }
an inflammatory response mediated by neutrophils that damages the intestinal - M# ] K1 S7 F- Y6 A
tissue and leads to proliferation and translocation of commensal bacteria. In
& H! ~6 }3 M; Ithis issue, Grainger et al. report that commensal bacteria help temper 9 o, n* N3 j7 V* a& N6 {- F
the inflammation caused by T. gondii by stimulating inflammatory
( c, y$ k8 S$ R* M# R. hmonocytes to release prostaglandin E2, which dampens neutrophil activity. The 4 Q! v& b& |/ k; v( c
cover depicts commensal bacteria in blue and intestinal villi in red in mice
9 _9 H5 `& I9 b, E$ finfected with T. gondii. Image credit: Lily Y. Koo and Michael J. Molloy. 5 s7 B" L) s) f' P3 }5 T4 r w
" B2 ? |1 _: i9 R7 ^ i$ ]9 [
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发表于 2013-6-8 20:34
发表于 2013-6-10 15:54
