2013-6-10 Developmental Cell

nero1981

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Volume 25, Issue 5
& E* S' n9 u1 ?$ V+ ?8 q" M! V) EOn the cover: Regulation of metabolic pathways plays a key role in controlling cell growth, proliferation, and survival in all tissues. The enzyme TIGAR acts as a fructose-2,6-bisphosphatase, promoting the pentose phosphate pathway to produce NADPH for antioxidant function and ribose-5-phosphate for nucleotide synthesis. The “eye of the tiger” on the cover shows H&E staining of TIGAR−/− intestinal tissue in an intestinal adenoma model. For more information about TIGAR's role in intestinal regeneration and tumor growth, see Cheung et al., pp. 463–477. Cover art by Pearl Lee.+ R0 u% j1 K; v* t: M

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anzhida0823

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yuheng

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cz200203

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MZzhang

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科研人

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石头111

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