《细胞》[Cell]13年6月20日出版pdf全文

nero1981

7 @! s1 {8 ^2 a' P5 ~Volume 153, Issue 7$ ^" U8 T: o$ \3 o2 Z1 ^# P: ~3 c2 |, Q9 ^5 `
On the cover: The mealybug Planococcus citri is host to two bacterial 2 K5 F: O# w. C
endosymbionts with extremely tiny genomes. These symbionts, Tremblaya and
+ g' z( e/ z' nMoranella, live exclusively in specialized insect cells. Remarkably, . ?% ^) i9 g0 d0 g. Q8 O; G; B
Moranella lives inside of Tremblaya; their relationship is the , R9 d( h3 o+ G% `" x3 T
only known bacteria-within-a-bacterium symbiosis. In this issue, Husnik et al. & S: [8 y7 Q" D
(pp. 1567–1578) show that this layered symbiosis is enabled by genes that have 3 c# r4 C+ a5 a6 C$ S
been horizontally transferred to the insect genome from diverse, historical
6 A1 A& \4 ^9 w  D. qbacterial infections. These transferred genes are overexpressed in the insect 8 |  `# r$ L- O/ |0 u
tissue housing Tremblaya and Moranella and seem to complement
% r7 ^( x0 ?+ T6 a0 g1 ^several symbiont activities. Importantly, these results show that, although the * c7 S# I- C- k: Y# J! A
Tremblaya genome rivals some organelles in terms of size and coding
. Q& m) G( Y9 O2 E4 L3 c3 scapacity, it has not arrived at this state by transferring its own genes to the " }% D: O" c0 \* M7 T! t
host genome. Photograph by Alex Wild, University of Illinois.
$ Z: Q' b) w4 E. |. @) O

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whyboy

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