《科学》[Science]13年7月26日出版pdf全文

nero1981

2013-7-26 Science& ~1 {4 G( U9 V, v2 _, P

/ w, o7 q* u; ^COVER Immunostained fluorescence microscopy image of memory
! \( o3 w6 r6 s' B2 P) m" yengram–bearing cells (red) in the dentate gyrus of a mouse hippocampus (image , Q: \, c# e- Y& m; e& D' k# c8 `
width: 1.5 millimeters). These cells were genetically tricked to express the 7 d& E# |0 X8 O7 D& V
protein channelrhodopsin-2 during memory formation, thus becoming responsive to
, h2 n7 C3 z% x; z/ Klight stimulation. When the cells were activated by light, the mice ' e, q: W, l9 J6 M( O+ v7 v5 G3 A
simultaneously associated a genuine memory with an undesirable event (a foot ' L8 [% A) d7 S6 p! e
shock) to create a new but false memory. See page 387. Image: : J- x7 S6 q4 n& @% `7 X
Xu Liu and Steve Ramirez
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