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本帖最后由 细胞海洋 于 2014-2-25 10:38 编辑
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' e7 |# [, ` O! eEdited by, k D6 q/ \0 A! h
M. BUCHANAN,University of Cambridge publisher
$ B! i7 ^! C) m4 S" b( eNetworks in Cell Biology aims to fill a yawning gap in the modern literature
' i, R+ {. o- F+ M2 l4 ]2 Bof systems biology. While a number of excellent texts at the graduate level cover6 H h4 Q$ n" Y, e2 F2 H: ^7 J
recent developments in cell biology, and others offer timely introductions to recent
" C3 G( J( f$ Jadvances in complex network science, no single volume yet focuses explicitly on. A, s8 n. H( R- D9 x
advances in our understanding of cellular networks. The present book offers an
% v y8 ^$ [% W yup-to-date snapshot of such work, aiming for a balance between empirical stud-7 {+ b% j, i! D# `0 M: f
ies and theory, which are natural complements in furthering knowledge in almost+ v3 I6 W8 [+ A9 i/ O- p7 b2 z7 k: a
any area of modern biology. What do we know about the qualitative and quan-
" I G3 Y* ~$ otitative structure and dynamics of genetic regulatory networks, or the network* t8 v$ ?7 D. }, ^% Z
biochemistry underlying cellular metabolism? What do empirical studies tell us
5 ^" ]6 k2 p) K# W, h- z! }about the large-scale architecture of protein–protein interactions, and what are the$ t, p* l, m! n5 `# J: ]6 p
key weaknesses and gaps in such data?What are the prospects for building realistic
9 ~) v4 i0 \( R" D4 jdynamical models for metabolic or regulatory processes, possibly with predictive
) S, r. T; O/ S1 o) F. Q$ o. ucapability?
7 r- Z/ ~! Z6 U7 l( F+ b: CThis volume covers these and other topics of current research in systems biology,; A5 A& A# J6 n9 k
with an emphasis on recent advances in complex networks science, and on how the
) w8 e" a/ d, s' |' \3 pmassive data now available in biology can help test and inform such theories in% u1 A# Q: i$ K. P
their application. With contributions from key leaders in both network theory and+ _9 r3 ^$ M0 }8 ] T+ ~! M
modern cell biology, this volume makes available in one publication the naturally
3 B: Z9 u+ S! M4 |2 Gdiverse range of studies supporting a unified view of biological networks that is/ s# _4 h' S6 S! Z" h& \
likely to be increasingly important in the future.* m! v# O, i* U( g9 C
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