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本帖最后由 细胞海洋 于 2014-2-25 10:38 编辑 1 H, A% @1 G$ y# b) n8 c
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Edited by& t/ B. k! |1 G; F+ i
M. BUCHANAN，University of Cambridge publisher- M2 L% U+ {& T3 D
Networks in Cell Biology aims to fill a yawning gap in the modern literature
$ U4 f) b9 j' r2 R9 Fof systems biology. While a number of excellent texts at the graduate level cover
( O( [2 Q+ n/ p) B( q6 b8 [recent developments in cell biology, and others offer timely introductions to recent, ]" [* W( L* {, \0 r, h. i- a
advances in complex network science, no single volume yet focuses explicitly on
0 g7 r2 |0 I0 A$ w* P% oadvances in our understanding of cellular networks. The present book offers an$ \+ T) i9 Q# D* B
up-to-date snapshot of such work, aiming for a balance between empirical stud-* F' }6 A( u3 B' b, V
ies and theory, which are natural complements in furthering knowledge in almost
+ t" O* G0 I4 r. t1 {any area of modern biology. What do we know about the qualitative and quan-; T: m' x8 h% z& ^) m, \
titative structure and dynamics of genetic regulatory networks, or the network
; |9 V# O' C7 w3 g _1 n& {- ?biochemistry underlying cellular metabolism? What do empirical studies tell us7 c7 y) p$ g4 A* C& n5 _! F
about the large-scale architecture of protein–protein interactions, and what are the
* c9 ?3 h5 ^0 a5 W/ q7 ?key weaknesses and gaps in such data?What are the prospects for building realistic
! g& @: t4 S+ [3 ^1 jdynamical models for metabolic or regulatory processes, possibly with predictive' ]& x& N6 f# Q# [0 r
capability?9 s; I: ]" m; I& c1 v
This volume covers these and other topics of current research in systems biology,# Q/ i! ~& ^5 V" b, A9 L
with an emphasis on recent advances in complex networks science, and on how the. X. }3 g3 ~) S5 V) o8 y$ g, O3 W. }* n
massive data now available in biology can help test and inform such theories in- l* C& H. D$ J$ R) _
their application. With contributions from key leaders in both network theory and3 T. T1 i4 ?8 J6 X! G$ f7 S
modern cell biology, this volume makes available in one publication the naturally' o' e$ t5 B* O+ Z3 p
diverse range of studies supporting a unified view of biological networks that is" P2 ]5 v4 g1 V Y
likely to be increasingly important in the future.! P# |, J9 x8 [( \8 e4 a: N
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发表于 2014-2-24 15:55
发表于 2014-2-27 00:04
