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2014年9月19日 Science6 |7 V7 o* V0 \2 Y, o3 b4 c+ O
+ i* y2 A& s% RCOVER Artist's impression of how a bacterial immune complex, called Cascade (foreground structure), from the CRISPR-Cas system recognizes invading DNA (red-blue-black strand) from a bacteriophage. Cascade, a complex of 11 proteins and a guide RNA, uses the sequence of the guide RNA to detect invading DNA. See pages 1452, 1473, and 1479 for a close-up look at Cascade before and after it binds to its target DNA.Illustration: Valerie Altounian/Science; protein coordinate data supplied by Scott Bailey# R: J8 x& h8 g8 z- t
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发表于 2014-9-24 20:18
发表于 2014-9-24 23:29
