Mechanisms of Disease Cancer Stem Cells

richy

Craig T. Jordan, Ph.D., Monica L. Guzman, Ph.D., and Mark Noble, Ph.D.
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The deepening of our understanding of normal biology has made
* K* w/ g4 q, n" dit clear that stem cells have a critical role not only in the generation of complex
; C- N& W2 i7 Smulticellular organisms, but also in the development of tumors. Recent( H; T" d, Q2 B
findings support the concept that cells with the properties of stem cells are integral
7 M1 [5 ]( ^% A$ f( Zto the development and perpetuation of several forms of human cancer.1-3 Eradication9 X  R: g& c4 F& G5 d  }$ a$ \
of the stem-cell compartment of a tumor also may be essential to achieve stable,
  g' p, S3 W: E1 @" d0 J4 W; g3 dlong-lasting remission, and even a cure, of cancer.4,5 Advances in our knowledge of% o8 N5 Y4 I& B4 N5 J  M
the properties of stem cells have made specific targeting and eradication of cancer
' \. `& q- S6 x% r6 Y6 g# q; i) sstem cells a topic of considerable interest. In this article, we discuss the properties
, @/ U; J. N% G  q- ]7 Mof cancer stem cells, outline initial therapeutic strategies against them, and present* @" N% @9 g# R  i3 Q
challenges for the future.3 {; V, W1 [. H4 w7 \) j
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efool

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Fischer3

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ahmusht

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Chris

like it
) d  ~5 V% r* l0 {thanks

barton_nyd

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yolanda_sea

谢了

hualin840518

很好！

hualin840518

很好！谢谢诶！

15816126

good