Mechanisms of Disease Cancer Stem Cells

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Craig T. Jordan, Ph.D., Monica L. Guzman, Ph.D., and Mark Noble, Ph.D.' R! {  K8 |- c( e0 S) j$ X' l! x

$ y) H5 d; q& Z. M4 C% ^The deepening of our understanding of normal biology has made
$ C& L2 i# x" d' Kit clear that stem cells have a critical role not only in the generation of complex
  a- \2 P6 p8 g% A: o8 O  S& j# Q. B: gmulticellular organisms, but also in the development of tumors. Recent3 Z/ _: y( }" r, L2 e4 f( M
findings support the concept that cells with the properties of stem cells are integral
$ r, ]# b& _) J9 D+ {4 wto the development and perpetuation of several forms of human cancer.1-3 Eradication: X- G. ]& p& k$ E
of the stem-cell compartment of a tumor also may be essential to achieve stable,
# B  r' t1 C& |2 t& N9 Zlong-lasting remission, and even a cure, of cancer.4,5 Advances in our knowledge of
7 O8 R  G- ?' d: d/ }8 Rthe properties of stem cells have made specific targeting and eradication of cancer
" d9 m! [; z: [; K  Q3 Bstem cells a topic of considerable interest. In this article, we discuss the properties
% {+ n' {- I- C! G; P) Iof cancer stem cells, outline initial therapeutic strategies against them, and present
& @$ Y$ p5 c  N7 zchallenges for the future.
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: ^9 j' k+ ]* x% J1 {附件是ｐｄｆ全文' d9 b9 d, L9 a! ^+ p" K
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efool

不错，很有价值

Fischer3

好东西，要顶！

ahmusht

have a look

Chris

like it
8 {  ]# J9 I& ~/ w6 H5 _thanks

barton_nyd

好东西，看看啊

yolanda_sea

谢了

hualin840518

很好！

hualin840518

很好！谢谢诶！

15816126

good