Mechanisms of Disease Cancer Stem Cells

richy

Craig T. Jordan, Ph.D., Monica L. Guzman, Ph.D., and Mark Noble, Ph.D.% I2 ^$ S6 A1 J" Y3 d
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The deepening of our understanding of normal biology has made+ y; n/ K& ~( _  _) u
it clear that stem cells have a critical role not only in the generation of complex
9 n! z3 z( _/ k" x6 Z9 ]- fmulticellular organisms, but also in the development of tumors. Recent" @- w- u8 Z- e$ J
findings support the concept that cells with the properties of stem cells are integral
4 G0 Z3 A! k" [! y' X5 V! hto the development and perpetuation of several forms of human cancer.1-3 Eradication; S5 M  P* k' J$ N9 Z& k
of the stem-cell compartment of a tumor also may be essential to achieve stable,
4 d2 n- v2 A* Mlong-lasting remission, and even a cure, of cancer.4,5 Advances in our knowledge of" x5 r: b& z  g' p' v  @; j" j
the properties of stem cells have made specific targeting and eradication of cancer
5 G6 C0 q2 o7 E  J& sstem cells a topic of considerable interest. In this article, we discuss the properties5 y! k& O2 I# X  U  l. x2 G" |( X
of cancer stem cells, outline initial therapeutic strategies against them, and present
! ^9 b6 Q6 C, l  W  K& Bchallenges for the future.
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- E( n8 q/ c  y" K附件是ｐｄｆ全文
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efool

不错，很有价值

Fischer3

好东西，要顶！

ahmusht

have a look

Chris

like it 5 S' X" q  v% k1 @- R
thanks

barton_nyd

好东西，看看啊

yolanda_sea

谢了

hualin840518

很好！

hualin840518

很好！谢谢诶！

15816126

good