|
- 积分
- 0
- 威望
- 0
- 包包
- 9
|
Craig T. Jordan, Ph.D., Monica L. Guzman, Ph.D., and Mark Noble, Ph.D.: F( b( R# ~6 d- L
9 D! s* t7 g4 MThe deepening of our understanding of normal biology has made
- Y$ H1 Z( h1 B5 g' C" x1 C0 dit clear that stem cells have a critical role not only in the generation of complex) e+ n5 d- \ u1 U- P, r
multicellular organisms, but also in the development of tumors. Recent* a& W, X' I& U2 L3 k
findings support the concept that cells with the properties of stem cells are integral" i0 A e4 V0 w# W$ W. b( G
to the development and perpetuation of several forms of human cancer.1-3 Eradication
0 R$ j' t+ C. \of the stem-cell compartment of a tumor also may be essential to achieve stable,
- d: f" T6 s! O+ N& ~long-lasting remission, and even a cure, of cancer.4,5 Advances in our knowledge of
& K+ H" @1 d( I+ ]the properties of stem cells have made specific targeting and eradication of cancer( O5 Z* |8 E7 ~7 \$ v# @% r7 e0 m
stem cells a topic of considerable interest. In this article, we discuss the properties
' E6 ?; d4 J) tof cancer stem cells, outline initial therapeutic strategies against them, and present/ a1 [7 z; H, P; r( N. P
challenges for the future.$ M1 F% C' Y7 O% k/ f( i
0 r+ L% ~4 I; _- F
附件是ｐｄｆ全文
5 L$ i) B- K2 k3 Y5 N1 |. s* G* \$ Y
[hide][/hide] |
附件: 你需要登录才可以下载或查看附件。没有帐号？注册
-
总评分: 包包 + 2
查看全部评分
|
发表于 2009-3-24 11:30
发表于 2009-6-3 13:46
