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本帖最后由 细胞海洋 于 2010-5-20 18:51 编辑
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经典高引用次数专著，很多要用到microarray分析技术的朋友可以参看下。
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在拿到你的microarray数据后，不知道分析的话面对上百的上调/下调基因、microRNAs表达谱变化或target genes会傻眼的
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" n3 G# T( v9 ^! Q7 _Editorial Reviews$ G2 W3 I8 _8 x1 u# M* T
Review
# N/ ?4 K8 U) X/ ?/ @"This book should be required reading for any (future and present) post-genomic researcher..."4 z |( g' K+ ?
— Sean D. Mooney, Briefings in Bioinformatics
8 _* z* V/ F4 H6 }& I+ `Product Description
4 f) X# p+ C4 y1 ^, ^9 J sFunctional genomics--the deconstruction of the genome to determine the biological function of genes and gene interactions--is one of the most fruitful new areas of biology. The growing use of DNA microarrays allows researchers to assess the expression of tens of thousands of genes at a time. This quantitative change has led to qualitative progress in our ability to understand regulatory processes at the cellular level. This book provides a systematic introduction to the use of DNA microarrays as an investigative tool for functional genomics. The presentation is appropriate for readers from biology or bioinformatics. After presenting a framework for the design of microarray-driven functional genomics experiments, the book discusses the foundations for analyzing microarray data sets, genomic data-mining, the creation of standardized nomenclature and data models, clinical applications of functional genomics research, and the future of functional genomics.( u6 X: E u6 {8 ]/ ]# }
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Hardcover: 326 pages 3 x; d% {" X" R: m
Publisher: The MIT Press; 1 edition (August 21, 2002) 5 I" }4 T6 u5 m- P# j* m* M
Language: English 9 L$ V, `5 `4 j
ISBN-10: 026211271X
6 ]' D( A/ q$ e/ @0 bISBN-13: 978-0262112710
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Introduction
7 l$ u; x6 C( Q介绍请参见Amazon) R$ L% G! e0 ?- C/ B$ e
http://www.amazon.com/Microarray ... cular/dp/026211271X Z8 }/ g. h1 t# f$ B+ [: j& k+ Y9 H
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发表于 2010-5-20 18:48
发表于 2010-5-21 13:26
