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本帖最后由 细胞海洋 于 2010-5-20 18:51 编辑 , c9 W2 L/ O$ h
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O$ x, g- i v; p) Q4 R经典高引用次数专著,很多要用到microarray分析技术的朋友可以参看下。
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在拿到你的microarray数据后,不知道分析的话面对上百的上调/下调基因、microRNAs表达谱变化或target genes会傻眼的
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Editorial Reviews
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_; e( i h& ]$ y9 y% ^. | P"This book should be required reading for any (future and present) post-genomic researcher..."
2 y5 q2 B5 q7 y+ c— Sean D. Mooney, Briefings in Bioinformatics
0 j+ H c( @- d6 c9 lProduct Description$ I2 u; s0 P, x" C, z9 Z
Functional genomics--the deconstruction of the genome to determine the biological function of genes and gene interactions--is one of the most fruitful new areas of biology. The growing use of DNA microarrays allows researchers to assess the expression of tens of thousands of genes at a time. This quantitative change has led to qualitative progress in our ability to understand regulatory processes at the cellular level. This book provides a systematic introduction to the use of DNA microarrays as an investigative tool for functional genomics. The presentation is appropriate for readers from biology or bioinformatics. After presenting a framework for the design of microarray-driven functional genomics experiments, the book discusses the foundations for analyzing microarray data sets, genomic data-mining, the creation of standardized nomenclature and data models, clinical applications of functional genomics research, and the future of functional genomics.
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Product Details- S" J6 ^8 d# h/ x
Hardcover: 326 pages
! ^6 e3 y: S4 t1 C0 {7 M0 JPublisher: The MIT Press; 1 edition (August 21, 2002) # c( \$ r' a7 D
Language: English ; @- h( c3 _! P% O. G4 z: b
ISBN-10: 026211271X
- W0 }0 _1 {- d' m& D) E, y9 RISBN-13: 978-0262112710 - ?4 e) i7 f3 L# q* G
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$ g9 }$ e1 ]: g U, J' ^Introduction
9 ^8 v x* y: C, u介绍请参见Amazon6 Y1 D/ J/ ~9 s2 U8 s
http://www.amazon.com/Microarray ... cular/dp/026211271X
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