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本帖最后由 细胞海洋 于 2010-5-20 18:51 编辑 ! s, D3 Y, Z: E( ~
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: f [; N4 y3 [7 C* w+ X0 D经典高引用次数专著,很多要用到microarray分析技术的朋友可以参看下。
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在拿到你的microarray数据后,不知道分析的话面对上百的上调/下调基因、microRNAs表达谱变化或target genes会傻眼的 , ~+ } s# v9 C
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Editorial Reviews/ v8 ^1 H7 K) G/ h
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"This book should be required reading for any (future and present) post-genomic researcher..."
U0 a B7 [0 R- h: g p! L5 `; j— Sean D. Mooney, Briefings in Bioinformatics
8 h) `. k; z, { J( V& L+ T0 vProduct Description
3 _" ~- b" I# QFunctional genomics--the deconstruction of the genome to determine the biological function of genes and gene interactions--is one of the most fruitful new areas of biology. The growing use of DNA microarrays allows researchers to assess the expression of tens of thousands of genes at a time. This quantitative change has led to qualitative progress in our ability to understand regulatory processes at the cellular level. This book provides a systematic introduction to the use of DNA microarrays as an investigative tool for functional genomics. The presentation is appropriate for readers from biology or bioinformatics. After presenting a framework for the design of microarray-driven functional genomics experiments, the book discusses the foundations for analyzing microarray data sets, genomic data-mining, the creation of standardized nomenclature and data models, clinical applications of functional genomics research, and the future of functional genomics.
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& H- Y8 k2 N* x. jProduct Details b6 @' y# o3 G" x" l
Hardcover: 326 pages + O: {, h* K) P9 v) h
Publisher: The MIT Press; 1 edition (August 21, 2002)
/ ]2 ?) q' J9 D. ULanguage: English - U5 q; ? T/ I/ X0 o* t
ISBN-10: 026211271X 9 g; a, `3 ~& a# D5 z
ISBN-13: 978-0262112710
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Introduction. u$ d6 q8 S M3 }
介绍请参见Amazon$ U: u$ u2 `/ u0 u
http://www.amazon.com/Microarray ... cular/dp/026211271X
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