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本帖最后由 细胞海洋 于 2010-5-20 18:51 编辑
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经典高引用次数专著,很多要用到microarray分析技术的朋友可以参看下。2 y) R% W+ l9 X$ a# o4 L8 n
: E' y# f! [- P在拿到你的microarray数据后,不知道分析的话面对上百的上调/下调基因、microRNAs表达谱变化或target genes会傻眼的 , I' }+ y& e! q$ X
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Editorial Reviews
! E( V0 T$ c& mReview
+ K& [4 r2 A- _: g- d: q4 \"This book should be required reading for any (future and present) post-genomic researcher..."
/ C4 Y8 R1 ?3 A( H2 i" Z9 `5 j# o& K# H— Sean D. Mooney, Briefings in Bioinformatics * s U" a& p2 P2 R8 k( C0 M6 @
Product Description4 U& H, t/ Q. [4 F' K4 Q0 U
Functional genomics--the deconstruction of the genome to determine the biological function of genes and gene interactions--is one of the most fruitful new areas of biology. The growing use of DNA microarrays allows researchers to assess the expression of tens of thousands of genes at a time. This quantitative change has led to qualitative progress in our ability to understand regulatory processes at the cellular level. This book provides a systematic introduction to the use of DNA microarrays as an investigative tool for functional genomics. The presentation is appropriate for readers from biology or bioinformatics. After presenting a framework for the design of microarray-driven functional genomics experiments, the book discusses the foundations for analyzing microarray data sets, genomic data-mining, the creation of standardized nomenclature and data models, clinical applications of functional genomics research, and the future of functional genomics.6 h8 d. y# U7 n' U
5 N9 l8 R% t- M3 |) nProduct Details
) g7 V+ ^. O! |' QHardcover: 326 pages
D u' o- g1 v5 s' \2 a1 APublisher: The MIT Press; 1 edition (August 21, 2002) # p+ i& u# H6 \# }
Language: English
" _9 y l9 W2 Y: m" f% q) u v# VISBN-10: 026211271X
. T G, D' H4 e% I1 OISBN-13: 978-0262112710
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Introduction* V1 h9 h: P' p: @
介绍请参见Amazon
# p* j1 Z- a6 |. lhttp://www.amazon.com/Microarray ... cular/dp/026211271X
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