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本帖最后由 细胞海洋 于 2010-5-20 18:51 编辑 ( W; v. e+ H$ M- X& r+ N
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经典高引用次数专著,很多要用到microarray分析技术的朋友可以参看下。
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在拿到你的microarray数据后,不知道分析的话面对上百的上调/下调基因、microRNAs表达谱变化或target genes会傻眼的 0 `' f6 m; j" n7 |2 \
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Editorial Reviews _ B* V3 _( k7 q: o9 t! ~
Review
( p" s6 H: E2 a, C& ]0 E"This book should be required reading for any (future and present) post-genomic researcher..."5 [+ P) x4 \' m1 u# B$ E; i
— Sean D. Mooney, Briefings in Bioinformatics ) _4 K- n# [1 @# {- Z& x: G- n
Product Description$ ]! x4 [' k2 {
Functional genomics--the deconstruction of the genome to determine the biological function of genes and gene interactions--is one of the most fruitful new areas of biology. The growing use of DNA microarrays allows researchers to assess the expression of tens of thousands of genes at a time. This quantitative change has led to qualitative progress in our ability to understand regulatory processes at the cellular level. This book provides a systematic introduction to the use of DNA microarrays as an investigative tool for functional genomics. The presentation is appropriate for readers from biology or bioinformatics. After presenting a framework for the design of microarray-driven functional genomics experiments, the book discusses the foundations for analyzing microarray data sets, genomic data-mining, the creation of standardized nomenclature and data models, clinical applications of functional genomics research, and the future of functional genomics.
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Product Details
& T! S7 b* ?) X& oHardcover: 326 pages . R% c& [: U" u' e8 D
Publisher: The MIT Press; 1 edition (August 21, 2002)
: D+ U( D0 Q* qLanguage: English
" i/ o+ K; q) h6 OISBN-10: 026211271X 2 y! J- R/ w6 E
ISBN-13: 978-0262112710
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Introduction. t; y& E* P5 O/ k
介绍请参见Amazon
$ u X F* j6 P, d; g7 Fhttp://www.amazon.com/Microarray ... cular/dp/026211271X
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