李凌松:胚胎干细胞

sciential

* e8 r9 m& a7 e7 w& Z- G4 G! W
, Y9 q+ f1 n/ d
李凌松*，王 莉1 w7 P/ w2 q& m7 H) ~
（北京大学干细胞研究中心细胞生物学系，北京 100871）
% y' Q9 O3 V# r' ~摘　要：胚胎干细胞具有自我复制并分化为人体各种功能细胞的潜能。胚胎干细胞具有的独特生物学
' l0 Q' z; t& v" v$ V  ?特性使其被广泛应用于生物学研究的各个领域，特别是发育学。同时，它潜在的医学应用也成为世界
& P' z5 M5 S4 \% M4 p范围内的研究热点。但是，由于人胚胎干细胞的来源为植入前的早期胚胎，人胚胎干细胞自诞生之日3 m5 s2 e. I7 X, |$ n
起便倍受争议。本文将从胚胎干细胞的来源、特性、鉴定标准、增殖机理、应用前景以及研究本身7 o3 v" Y- C) F7 z
涉及的伦理学争论给予概述。. V* y* @+ }' R9 V1 y
关键词：胚胎干细胞；自我更新；分化；鉴定；胚胎生殖细胞；应用& p' X5 p& L/ }0 J2 B
中图分类号：Q813　　文献标识码：A
% z$ h3 g; `/ s$ J- z4 ?Embryonic stem cells
1 h) t1 @2 t6 ~7 I/ u$ qLI Ling-Song*, WANG Li
( Q4 s  F1 y6 G+ D(Department of Cell Biology, Stem Cell Research Center, Peking University, Beijing 100871)
9 j9 K7 m- G# d2 b6 V2 g( CAbstract: Embryonic stem (ES) cells are able to self-renew and differentiate into all kinds of human cells. Due to$ F) e* D; k( a0 X. y* ~
their unique properties, ES cells are used in diverse fields of biological research，particular in developmental
4 I: z9 U% o! {) U  }biology. Meanwhile, their potential medical application become a research hot-spot worldwidly. Since preimplantation3 |! Y  T' H+ O3 v
eggs are sources to generate ES cells, the use of embryonic stem cells is therefore controversial.3 k2 K  m+ s! Z3 x/ @/ @
This review will outline characterization of ES cells, regulation of self-renewal, and the applications of the cell
- n6 b7 q1 @" Yin treating diseases, as well as ethical issues related to human ES cells research.. ~: d0 X% H/ V! ]3 q! r( T
Key words: embryonic stem cells; self-renewal; differentiation; characterization; embryonic germ cells;
( ~0 Z9 w5 o% v6 K9 ?. X3 v9 J. |, x" [0 P2 n  b: t% [2 i
附件为全文，请大家支持一下 回复本贴就可以下载了: s8 w0 e) c' A' U4 P  }; [5 U

7 g7 W" W1 S( t! t

liyaodong

好人

deciple

好书

zhangl

好人，好书

mscbj

好文，谢了！

czzhaozhu

Thanks a lot!

njrmcljf

支持

cortex

xiexie

ouyi2738

xiexie

s08060882

看一下！