PDF电子书：Great Experiments

woosheng

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3 x& V! a+ S  b4 n7 ^Great Expeiments: Z7 E  L$ l/ J2 O5 J7 ]

5 y+ Q) x0 x1 K2 w; v: ^1 \) JGE.1.1 Norton Zinder - The discovery of transduction
( t( T% u  v3 [  EGE.1.2 Charles Yanofsky - Gene-protein colinearity
. X% q% U  c% e3 rGE.1.4 Vernon Ingram - The sickle cell story ca. 1956
( |0 Y! q6 [" r8 G7 NGE.2.1 Mark Ptashne - Isolation of repressor* g  ^! m7 J9 V) Z* V1 _; E
GE.2.3 Mark Ptashne, Grace Gill and Roger Brent - Modularity of eukaryotic transcription activators+ z& y2 u3 t; ]$ X4 [5 r9 D
GE.2.6 Nina Fedoroff - The discovery of transposition1 U6 O. f$ j; ~8 T3 }) h
GE.3.3 Michael Wigler - Origins of transfection  DNA transfer, stable integration, and function  k( G4 C- R- i6 z
GE.3.4 Mario Capecchi - Gene targeting  Altering the genome in mice
( y7 B/ T9 w/ FGE.4.1 Phillip Sharp - The discovery of RNA splicing
# j( H+ c+ l; D; n; d: B. d+ I* F) ?$ V+ B) [GE.4.2 Richard Roberts - The discovery of split genes and RNA splicing" u: p# \6 X( e! X* P: Y9 m( q
GE.4.3 Joan Steitz - The discovery of snRNPs and their role in splicing
( g7 c5 L7 n9 o3 `5 V2 SGE.4.4 Thomas Cech - RNA catalysis
% }8 U) M6 X8 S( x: l% q7 F# KGE.4.5 Harry Noller - Evidence that peptidyl transferase is RNA' d. y) ?) L# n9 _1 M
GE.4.6 Tamás Kiss - Small nucleolar RNAs guide rRNA modification0 O, Q' b' Y6 x9 y% g
GE.4.7 Rob Benne - RNA Editing: \1 j1 j# N6 f) N. @
GE.4.8 Joan Steitz - rRNA-mRNA base pairing selects translational initiator regions in bacteria
& W2 R7 L- o0 I/ nGE.5.1 Robert L Baldwin - Anfinsen's experiment—Spontaneous protein folding
; s2 [% z  M) K  mGE.5.2 Arthur Horwich - The discovery of protein folding by chaperonins
  Z, R  {( `+ M1 F6 u. `( g, IGE.5.3 Avram Hershko and Aaron Ciechanover - Ubiquitin conjugation as a proteolytic signal  The first experiments2 I. S2 j# H; c5 |" w
GE.6.3 James Rothman - The cell-free reconstitution of vesicle transport6 q; K# j6 {4 t
GE.6.5 Hugh Pelham - The discovery of the KDEL retrieval signal: h- ^0 `# N! G# z) n
GE.6.6 James Rothman and Thomas Sollner - The SNARE complex and its role in the specificity of membrane fusion9 F- N$ Q. X7 O2 Z$ N  ^
GE.6.7 Joseph Goldstein and Michael Brown - The discovery of the LDL receptor  Clues to receptor-mediated endocytosis# }  [, Y1 G0 d: \' {3 k7 m
GE.7.1 Xiaodong Wang - The role of cytochrome c in apoptosis
" j+ w$ |1 g) T, a, M( b5 p9 QGE.7.5 Yasutomi Nishizuka - The discovery of protein kinase C
9 f+ e! c) \) W$ HGE.8.1 Yoshio Masui - The discovery of MPF
  ?: X& L/ M2 u! k& [GE.8.2 Paul Nurse - The discovery of cdc2 as the key regulator of the cell cycle
& O& j8 r- I9 aGE.8.3 Tim Hunt - The discovery of cyclins
2 ?4 c7 ^) U$ v, T6 |$ D2 {GE.8.4 Lee Hartwell - Cell cycle genes
' h* T" |) W+ i  v5 c" x0 CGE.8.5 Ted Weinert - The origins of cell cycle checkpoints0 m! }$ t8 A9 s
GE.9.1 Howard Green - The story of 3T3 cells  A voyage of discovery without an itinerary
3 s& N2 p, `! w$ O% @+ cGE.9.2 Jerry Shay and Woodring Wright - Immortalizing human cells with telomerase
) p- T6 B) m% p* g% r$ O& q. DGE.9.3 Marc Kirschner and Tim Mitchison - Dynamic instability of microtubules
7 g0 L6 I  l* k$ N! g. p6 K" V6 QGE.10.1 Steven Martin - Identification of a retroviral transforming gene# ^3 G% W* s) \& G9 n# y, D
GE.10.3 Robert Weinberg -  The discovery of oncogenes in human tumors$ K8 |; N' J$ l% I( `5 c
GE.10.4 Arnold Levine - p53 is a tumor suppressor gene
; `& c0 Q# l* Y2 s! `9 e& a. ^7 KGE.11.1 John Gurdon - The conservation of the genome and nuclear reprogramming in Xenopus: {( [  B- i# _0 }1 K
GE.11.3 Ralph Brinster and Richard Palmiter - Transgenic mice  Expression of foreign genes in animals
- F3 L, g; u! w5 {- U6 WGE.11.4 Davor Solter - Nonequivalence of parental genomes and the discovery of imprinting
7 L2 F3 v3 v% O3 @GE.11.9 Claudio Stern - Spemann and Mangold's discovery of the organizer
/ C$ G4 G5 J1 zGE.11.10 Mary Lyon - The discovery of X-chromosome inactivation. {: \! e: q5 d1 p' l2 x
GE.11.11 Jim Smith - Growth factors as developmental signals
* F& {5 N9 C& W6 o' N% b% I: fGE.12.1 Hugh McDevitt - The discovery of genetic linkage of transplantation antigens and the immune response
' }5 r6 q- M4 \9 }3 aGE.12.5 David Schatz - Identification of the V(D)J recombination activating genes, RAG1 and RAG2
# _% Y( ~) u& s8 j9 x% jGE.12.8 Stephen M Hedrick and Mark M Davis - Identifying T cell antigen receptor genes
3 O8 z8 E- `+ s! j; M& s" DGE.12.10 Harald von Boehmer - Lymphocyte survival and lineage determination through positive selection
6 }* N: t7 _' J2 Q7 ~- Y4 z4 m4 sGE.13.1 Sir Andrew Fielding Huxley O.M., Sc.D. (hon.), F.R.S. - Determining the full size of the action potential

wgydys

thanks

cz200203

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资料老了点，而且好象不全噢

lyf910919

呵呵

sky蓝

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红旗

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剑啸寒

呵呵 高高实在是高~~~~~  

123456zsz

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