PDF电子书：Great Experiments

woosheng

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Great Expeiments
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8 c/ r+ W$ J1 ?3 B5 M# RGE.1.1 Norton Zinder - The discovery of transduction
8 n# W* B2 G1 A% \# OGE.1.2 Charles Yanofsky - Gene-protein colinearity0 K3 H# g4 Y' A) }2 x! {3 d
GE.1.4 Vernon Ingram - The sickle cell story ca. 1956, M" j. V$ ~3 O+ o
GE.2.1 Mark Ptashne - Isolation of repressor% r5 `* E7 \% w# a; g( V
GE.2.3 Mark Ptashne, Grace Gill and Roger Brent - Modularity of eukaryotic transcription activators7 W% F3 y" w4 C& ]
GE.2.6 Nina Fedoroff - The discovery of transposition
  L# q- o1 c2 L1 AGE.3.3 Michael Wigler - Origins of transfection  DNA transfer, stable integration, and function
* d1 A0 M. j4 `. q' z% [* G) iGE.3.4 Mario Capecchi - Gene targeting  Altering the genome in mice
5 t$ S. V7 ]' z: `9 mGE.4.1 Phillip Sharp - The discovery of RNA splicing
. U! V  ]6 D4 b5 `5 ]4 mGE.4.2 Richard Roberts - The discovery of split genes and RNA splicing
4 v; `1 y& q+ `GE.4.3 Joan Steitz - The discovery of snRNPs and their role in splicing
/ b( D" e  ~0 ^' F% yGE.4.4 Thomas Cech - RNA catalysis
5 ~4 E- Z2 J9 Z# k; pGE.4.5 Harry Noller - Evidence that peptidyl transferase is RNA2 h- v" w# v$ W/ B  i3 I6 V0 N
GE.4.6 Tamás Kiss - Small nucleolar RNAs guide rRNA modification6 W# f, ^7 b( b# g# i- M! G3 ]9 o
GE.4.7 Rob Benne - RNA Editing
: F! b5 k& e! S2 dGE.4.8 Joan Steitz - rRNA-mRNA base pairing selects translational initiator regions in bacteria" Q/ W+ x/ t, h: L6 v- `+ E; B( |; b& _
GE.5.1 Robert L Baldwin - Anfinsen's experiment—Spontaneous protein folding
* r! b0 Z4 C4 I3 ~, hGE.5.2 Arthur Horwich - The discovery of protein folding by chaperonins. H3 j8 k4 [/ _" Q( y: w
GE.5.3 Avram Hershko and Aaron Ciechanover - Ubiquitin conjugation as a proteolytic signal  The first experiments
4 Y, u: A8 e+ fGE.6.3 James Rothman - The cell-free reconstitution of vesicle transport' i$ Z9 j  q- L+ c
GE.6.5 Hugh Pelham - The discovery of the KDEL retrieval signal5 o% K. P8 K- [! r' o/ z- U6 L2 P
GE.6.6 James Rothman and Thomas Sollner - The SNARE complex and its role in the specificity of membrane fusion
# N1 ~' \0 k4 T# G0 x; m9 ~GE.6.7 Joseph Goldstein and Michael Brown - The discovery of the LDL receptor  Clues to receptor-mediated endocytosis3 z: y+ L# Q; X# X% h. v+ V
GE.7.1 Xiaodong Wang - The role of cytochrome c in apoptosis
+ z3 p5 {" y; R. P+ }; ZGE.7.5 Yasutomi Nishizuka - The discovery of protein kinase C
: \* c* y) ^4 q# A; uGE.8.1 Yoshio Masui - The discovery of MPF) K0 H2 x& [1 k2 E" ?3 c  R( X. b# D
GE.8.2 Paul Nurse - The discovery of cdc2 as the key regulator of the cell cycle
0 F) {9 @  d/ G5 s* a1 [* DGE.8.3 Tim Hunt - The discovery of cyclins1 {: f5 v6 \0 y; y' U+ J5 M
GE.8.4 Lee Hartwell - Cell cycle genes" o( d8 c  J: Z- s8 h4 B. }; `
GE.8.5 Ted Weinert - The origins of cell cycle checkpoints
1 n- b$ \8 u, Y" m" i) OGE.9.1 Howard Green - The story of 3T3 cells  A voyage of discovery without an itinerary
/ F4 X0 \! N6 i3 R( oGE.9.2 Jerry Shay and Woodring Wright - Immortalizing human cells with telomerase* B% o" Q- |. L1 [$ g
GE.9.3 Marc Kirschner and Tim Mitchison - Dynamic instability of microtubules) R1 ~6 f/ J! k$ T* Q- d; c4 O
GE.10.1 Steven Martin - Identification of a retroviral transforming gene% I: s2 y4 K  p% t
GE.10.3 Robert Weinberg -  The discovery of oncogenes in human tumors2 |) i9 x, l! S" K' A- }2 E1 d
GE.10.4 Arnold Levine - p53 is a tumor suppressor gene- {+ r) c' B* C) e
GE.11.1 John Gurdon - The conservation of the genome and nuclear reprogramming in Xenopus7 Z6 k1 v3 w- d3 H- T, M2 c' F4 h, F
GE.11.3 Ralph Brinster and Richard Palmiter - Transgenic mice  Expression of foreign genes in animals3 _7 s: W! w9 ?# ?
GE.11.4 Davor Solter - Nonequivalence of parental genomes and the discovery of imprinting
# e$ G+ C7 \9 B  z# [1 uGE.11.9 Claudio Stern - Spemann and Mangold's discovery of the organizer
+ o8 U" }7 j2 FGE.11.10 Mary Lyon - The discovery of X-chromosome inactivation
+ i, T/ ^2 |  N' s2 o3 O% f# _GE.11.11 Jim Smith - Growth factors as developmental signals  @& Z' o# u) l3 g& j, _! G- d5 t
GE.12.1 Hugh McDevitt - The discovery of genetic linkage of transplantation antigens and the immune response
* e* l) v/ }$ RGE.12.5 David Schatz - Identification of the V(D)J recombination activating genes, RAG1 and RAG21 a% r- D7 k' k- J. J7 y3 R
GE.12.8 Stephen M Hedrick and Mark M Davis - Identifying T cell antigen receptor genes
# f( Q) J! X1 Q% f3 J9 PGE.12.10 Harald von Boehmer - Lymphocyte survival and lineage determination through positive selection
" c3 I. x" N# s" x3 l8 y! f8 A* n5 SGE.13.1 Sir Andrew Fielding Huxley O.M., Sc.D. (hon.), F.R.S. - Determining the full size of the action potential

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thanks

cz200203

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资料老了点，而且好象不全噢

lyf910919

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sky蓝

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红旗

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剑啸寒

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