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2012年11月 Nature Medicine1 G z' ~0 }$ H# x
8 l& o7 z8 g. P6 \. lIn this issue, Andrew Weng and his colleagues uncover a new
3 O3 J! D- t& u9 Amechanism by which oncogenes regulate leukemia stem cells. Notch-driven
$ G7 Y1 E, F: W+ g7 u1 K( f S5 L* s( zinactivation of PKCθ attenuates the accumulation of 9 } S: H0 V* h3 [* j) f
reactive oxygen species to lower oxidative stress in the stem cell population of 1 z& J6 z6 H7 p0 ~( s" v
T cell acute lymphoblastic leukemia (ALL), contributing to tumorigenesis. The 2 A7 U* ^- @/ B1 N2 P8 V# d
image shows an electron micrograph of erythrocytes and lymphocytes from a $ \" H4 t3 C+ a
patient with ALL. Photo by Steve Gschmeissner/Science Photo Library.
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5 N2 A- e/ d9 m$ {3 ~[hide][/hide] |
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发表于 2012-11-10 12:55
发表于 2012-11-12 16:35
