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2013-7-26 Science
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COVER Immunostained fluorescence microscopy image of memory
* i8 N- a+ g2 l6 }3 a7 pengram–bearing cells (red) in the dentate gyrus of a mouse hippocampus (image
4 E5 k/ G, J2 Iwidth: 1.5 millimeters). These cells were genetically tricked to express the
z3 m4 S/ H- L; I6 ^$ fprotein channelrhodopsin-2 during memory formation, thus becoming responsive to
7 Z" k/ E' ~4 O7 clight stimulation. When the cells were activated by light, the mice
% W9 {" N' W0 m }% Y8 Gsimultaneously associated a genuine memory with an undesirable event (a foot
9 F- X- a3 X" c8 ^; Bshock) to create a new but false memory. See page 387. Image:
5 M9 R6 g- o7 x1 @' nXu Liu and Steve Ramirez & C* _6 p) B/ o- P# z8 ?4 q% _4 [
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