Cell进展：Noncoding RNAs: The Missing “Linc” in p53-Mediated Repression

轩辕之客

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5 ]" O4 n; d* U! T$ R非编码RNA与P53介导的细胞凋亡：( A! m: t$ j4 t" e4 D, ~) D

3 w" v- ^! R% nRecord Number: 1065- E# s; h! {+ c  M" ?
Author: A. M. Barsotti and C. Prives
1 C. r& N% c( D) fYear: 2010! W8 ?  x! f5 n5 y
Title: Noncoding RNAs: The Missing "Linc" in p53-Mediated Repression
% C% z! ~) l; ^. L$ AJournal: Cell
; ?: L2 ^& z, j+ S3 v  Q: uVolume: 1423 e7 ^- I: l$ f6 [' f# d
Issue: 3
2 _# c$ M7 G! `- ^. JPages: 358-360; f* W) Q$ |' U. ?: {2 N
Epub Date: 2010/08/105 y7 S5 O5 U) D/ }7 e. s7 l
Date: Aug 6
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Noncoding RNAs: The Missing “Linc” in p53-Mediated Repression0 }. w0 t- g/ k; T4 n

: g4 |7 U8 }$ g5 g3 TThe tumor suppressor protein p53 coordinates the cellular response to stress through regulationof gene expression. Now, Huarte et al. (2010) identify a long intergenic noncoding RNA as a newplayer in p53-mediated repression of genes involved in apoptosis.