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肝细胞 hepatocytes
' p6 Y' X6 u- F" X1 Rashid, S.T. et al. Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells. The Journal of Clinical Investigation 120, 3127-3136 (2010). 8 G* l; D' Y# D+ S
2 Ghodsizadeh, A. et al. Generation of Liver Disease-Specific Induced Pluripotent Stem Cells Along with Efficient Differentiation to Functional Hepatocyte-Like Cells. Stem Cell Reviews and Reports 6, 622-632 (2010).
% L: Q3 ?1 W% V' L& W3 Sullivan, G.J. et al. Generation of functional human hepatic endoderm from human induced pluripotent stem cells. Hepatology 51, 329-335 (2010)./ M9 e+ j9 K9 P' W
4 Si-Tayeb, K. et al. Highly efficient generation of human hepatocyte–like cells from induced pluripotent stem cells. Hepatology 51, 297-305 (2010).% e: P. ~. L7 i
5 Song, Z. et al. Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells. Cell Res 19, 1233-1242 (2009).
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! z' M! y; X( h" {2 _2 E R- S神经细胞" `* m" m q: `% T: i: l
neural crest precusors0 T3 n9 H5 ?. d/ {
6 Lee, G. et al. Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs. Nature 461, 402-406 (2009).
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neuroepithelial cell
3 E* y; w2 s5 X6 |& q+ G! e9 H- v7 Hu, B.-Y. et al. Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency. Proceedings of the National Academy of Sciences 107, 4335-4340 (2010)
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motor neurons【包括文献7】
7 M# B' u; [' F* M8 Dimos, J.T. et al. Induced Pluripotent Stem Cells Generated from Patients with ALS Can Be Differentiated into Motor Neurons. Science 321, 1218-1221 (2008).
: v4 F; t" z) K) j9 P9 Ebert, A.D. et al. Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature 457, 277-280 (2009).
4 m' X: A/ s7 [+ f6 W7 c6 S10 Chambers, S.M. et al. Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling. Nat Biotech 27, 275-280 (2009).
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dopaminergic neurons of the midbrain 【包括文献10】
! f8 S/ q( p$ t$ I11 Soldner, F. et al. Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors. Cell 136, 964-977 (2009).
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! Q3 l" [* p( Jglia 【包括文献7,8】. ?# O- g- C% ~( v: j# I0 y+ w$ z
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视网膜细胞
( g5 `: o7 |( iRetinal Pigmented Epithelium; Y' d, I3 w- n
12 Buchholz, D.E. et al. Derivation of Functional Retinal Pigmented Epithelium from Induced Pluripotent Stem Cells. Stem Cells 27, 2427-2434 (2009).- b# o- L9 t; T' W# d
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retinal cells
: {. g& v# z, N6 i13 Osakada, F. et al. In vitro differentiation of retinal cells from human pluripotent stem cells by small-molecule induction. J Cell Sci 122, 3169-3179 (2009).
* ^9 A% i. |* a5 `: K) |4 v14 Meyer, J.S. et al. Modeling early retinal development with human embryonic and induced pluripotent stem cells. Proceedings of the National Academy of Sciences 106, 16698-16703 (2009).
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2 [* b9 r9 m5 A& m心肌细胞 cardiomyocytes2 e& j8 W3 Z: l4 G2 N; h/ \
15 Moretti, A. et al. Patient-Specific Induced Pluripotent Stem-Cell Models for Long-QT Syndrome. New England Journal of Medicine 363, 1397-1409 (2010).
+ m3 V6 p: j: ]( r/ A4 D16 Carvajal-Vergara, X. et al. Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome. Nature 465, 808-812 (2010).
# r) T+ e# _- H% o17 Zhang, J. et al. Functional Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells. Circ Res 104, e30-41 (2009).
9 ]7 O' B5 d9 n! V1 J18 Zwi, L. et al. Cardiomyocyte Differentiation of Human Induced Pluripotent Stem Cells. Circulation 120, 1513-1523 (2009).' o, A9 f6 f6 T2 t3 E4 g( i Q
9 ^+ I4 @ C0 l' \血管和血液相关细胞
+ _# w* X# I8 ]haematopoietic progenitors, Z5 G8 }, R u% A$ T8 R( s% [
19 Ye, Z. et al. Human-induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disorders. Blood 114, 5473-5480 (2009).
% N$ t8 t% x+ O- \9 B$ x. l20 Raya, A. et al. Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells. Nature 460, 53-59 (2009).; {% r1 r6 P+ D/ B; l* l0 c
8 o' ^' c/ G2 Y2 l( k$ a' k6 {, I. nblood cells, W3 C# u+ M- O2 T! E; t% ]5 a% U
21 Choi, K.-D. et al. Hematopoietic and Endothelial Differentiation of Human Induced Pluripotent Stem Cells. Stem Cells 27, 559-567 (2009).$ m) j$ @- O4 s( d B5 n
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vascular endothelial cells【包括文献21】
% H) f% |# z! t* I, F5 q22 Feng, Q. et al. Hemangioblastic Derivatives from Human Induced Pluripotent Stem Cells Exhibit Limited Expansion and Early Senescence. Stem Cells 28, 704-712 (2010).1 G6 U* V( R4 X" o) D
23 Taura, D. et al. Induction and Isolation of Vascular Cells From Human Induced Pluripotent Stem Cells--Brief Report. Arterioscler Thromb Vasc Biol 29, 1100-1103 (2009).8 {1 ~6 j" u; i3 {
9 c$ d) K2 \& X" p) v# D& `2 {: e胰岛素产生细胞 insulin-producing cells' j: n9 m0 }, D9 U
24 Maehr, R. et al. Generation of pluripotent stem cells from patients with type 1 diabetes. Proceedings of the National Academy of Sciences 106, 15768-15773 (2009).
1 I8 ~1 J1 F: t25 Zhang, D. et al. Highly efficient differentiation of human ES cells and iPS cells into mature pancreatic insulin-producing cells. Cell Res 19, 429-438 (2009).) y( b l& d% P
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原生殖细胞 primordial germ cells
2 w, ~, M& j' Q* t26 Park, T.S. et al. Derivation of Primordial Germ Cells from Human Embryonic and Induced Pluripotent Stem Cells Is Significantly Improved by Coculture with Human Fetal Gonadal Cells. Stem Cells 27, 783-795 (2009).3 U9 v$ u& T7 n5 N$ w& y2 U
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脂肪细胞 adipocyte2 l( G$ X9 V& Q$ q1 k/ {
27 Taura, D. et al. Adipogenic differentiation of human induced pluripotent stem cells: Comparison with that of human embryonic stem cells. FEBS Letters 583, 1029-1033 (2009).
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& a5 \& o2 {8 d! W! j+ e5 j& _可能会有失误的地方,见谅!3 }2 H/ w3 P/ B1 H2 Y
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