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Cell-Based Assays for High-Throughput Screening: Methods and Protocols (Methods in Molecular Biology)
& {* P) z, N+ fBy Paul A. Clemons, Nicola J. Tolliday, Bridget K. Wagner
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, N/ T( C$ T6 c/ Q ~Publisher: Humana Press 9 s2 i! m9 _* r7 H* G3 ? `
Number Of Pages: 248 ) z+ c+ Y+ S3 c
Publication Date: 2009-04-21
M4 @7 N: S; r1 JISBN-10 / ASIN: 1603275444
7 S6 F! E3 L+ o1 `5 [ISBN-13 / EAN: 9781603275446 . F- c) T! Z" `, _* N! Y
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$ A+ t1 c. q- n; n; y7 FProduct Description:
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- \+ V$ y' n2 T2 L4 HAs the use of high-throughput screening expands and creates more interest in the academic community, the need for detailed reference materials becomes ever more pressing. Cell-Based Assays for High-Throughput Screening: Methods and Protocols aims to fill an important part of this need by providing an easily accessible reference volume for cell-based phenotypic screening. Leading researchers in the field contribute state-of-the-art methods with actionable protocols covering four major areas of study: model biological systems, screening modalities and assay systems, detection technologies, and approaches to data analysis. Written in the highly successful Methods in Molecular Biology™ series format, each chapter includes a brief introduction to the subject, lists of necessary materials and reagents, step-by-step laboratory protocols, and a Notes section detailing tips on troubleshooting and avoiding known pitfalls.# z& j" t J i) S/ }1 t$ `! R
0 q6 r" K* w3 h: S9 j7 Q& DCutting-edge and easy-to-use, Cell-Based Assays for High-Throughput Screening: Methods and Protocols presents an overview of relevant approaches, enabling the direct application of existing methods to new discoveries while also inspiring researchers to approach their screening projects in a conceptually modular fashion, enhancing the power to discover through new combinations of existing approaches.
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