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- 积分
- 265
- 威望
- 265
- 包包
- 543
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可是这个版本（如果是，我就给你下）：
J/ x. L# h, d! ]Table of Contents: j1 Y" |6 ]" i o$ s* V
" S9 x; F5 H9 {8 ~- E8 `
I. Principles of Developmental Biology4 u r9 D7 N' n$ Y* b# r
$ E3 ?6 S$ L0 |# k" o
1. Developmental biology: The anatomical tradition' g6 G2 Y$ j0 p: \5 M; I
New techniques of mathematical modeling of development
! T; w: T6 |: o% Q9 [! d' Z7 F2. Life cycles and the evolution of developmental patterns
0 Y* }9 }" }+ C( C) F( |Recent advances in planarian regeneration
, D! b) I5 q0 T0 h& p3. Principles of experimental embryology- Z' q, D! d/ K9 Z
4. The genetic core of development
3 v7 j y [& V' p5. The paradigm of differential gene expression
! _4 h+ F( C' bHistone modifications1 S' t. `3 b- M/ O' ^
MicroRNAs+ N8 K; g8 ^: E# |& m
Pioneer transcription factors
. v+ q1 _1 R( A! m8 kMammalian cloning and methylation patterns
6 z4 q' Y/ l+ y! Z; u) n6. Cell–cell communication in development K+ ^) c1 ~: V# n
Stem cell specification and stem cell niches$ a3 f# [, Z5 B3 G/ u3 b
Morphogenetic regulation by cadherins6 L" ^+ ^' y( |- r9 m/ ]
Noncanonical Wnt pathways: W1 J& a6 o' i0 M( f2 E) T
Dependence receptors and apoptosis% D' V2 Z; J* _( `+ V4 l
Community effect and autocrine factors
/ U! B$ @. D' W: l% x X3 z+ |- [. y3 ?8 l$ t ^1 c
II. Early Embryonic Development
+ C$ d; I, `6 H {1 e
7 F' [4 ~. g& A7 T1 A- X# Y7. Fertilization: Beginning a new organism* f! b" M& p" {, D( e. q0 T* _4 Y
Cortical granule components
8 e+ b) u) H/ a: y1 S ENew mammalian sperm–egg binding model
) U% T' f$ [: w! R9 R# f# ~Mammalian sperm chemotaxis and thermotaxis
$ [2 o7 ~% p3 V7 h7 CMechanisms of sea urchin sperm chemotaxis
0 J' k% V! Y/ ~0 VSea urchin bindin receptor
1 a/ b; M6 S. @/ zOocyte translation inhibitors and their removal
O* N/ E9 T7 b. O: w3 @New hypotheses of sperm activation2 W. C, _9 X7 _3 a
Mammalian sperm–egg fusion
! S0 b! y, x( i1 j8 ]5 O8. Early development in selected invertebrates) ^2 \* D! j1 _
Wnt and Nodal in sea urchin axis specification
9 A# B0 x, |! m; F0 |& MCoiling genetics of snail embryos7 ?) Y6 d2 `' j- L, [& @' j# V/ F
Functions of tunicate yellow crescent
0 a& [5 q% o5 q; u8 hRoles of FGFs in tunicate development
' U$ U/ b F6 G# ] `, x8 G! x8 ?Tunicate heart development
. q' ?4 E7 }- t9. The genetics of axis specification in Drosophila0 P6 L+ T4 E. }5 z5 \
FGF signals and Drosophila mesoderm formation. y5 J6 P1 Q) d5 G
Transport of Nanos and Bicoid messages to opposite ends of the fly oocyte# f) G) w: q' @ r
New model for gap protein stabilization0 h# y+ z4 Q! P9 O
10. Early development and axis formation in amphibians
/ J7 w7 y% [8 u% t4 DNew models for organizer formation in Xenopus
. }% n W! u4 x* ]: LNew model for mesoderm specification in Xenopus6 Z0 b0 M' l) i5 i& m
11. The early development of vertebrates: Fish, birds, and mammals! M! a. [# {& n3 S! {
Maternal effect mutations in zebrafish- G' P+ z- B. T
Neurulation in zebrafish
1 e" m1 {7 ~) e" W, R# D" n- g6 @* BRetinoic acid in anterior–posterior axis specification in chordates. P) \% V# {) [! h7 N; y
Ciliary movements and left–right axis specification in vertebrates
6 i/ I9 a* R) v/ O& b& g; WRole of Cerberus in chick head formation
* ~& N6 z7 M$ z& U P0 j: mMesoderm specification and migration in chick gastrulae
) _# q" E3 E4 SFGF and cell fate in chick and mammalian epiblasts
" A+ ]2 M7 M" F# P, u) MInduction of pluripotency in mammalian inner cell mass blastomeres
4 A1 K- j# R1 I& `Homeotic transformation in mammals due to total Hox paralog knockouts5 e6 i$ h$ L' y6 @! @
Controversy over blastocyst polarity in mammals( `" d0 ^' ?( x4 G! R: H: ?# S
Folate receptors and teratogens affecting neurulation G- s/ s/ ]9 q' h
1 K n+ S1 |/ K; E
III. Later Embryonic Development8 c9 p# @; R7 ~- V( F
& F* {7 T4 @+ Q" V& u7 K5 g12. The emergence of the ectoderm: Central nervous system and epidermis
) x3 f2 ~! v1 ]Genes specifying neural fate
% c1 W5 U; Y+ oHuman-specific genes specifying brain growth
/ p* d3 K- U7 d) `4 Y# m( F* ~Progressive myelination of the human brain- u( R9 n5 X' a4 Z# m% t+ P S
Neural stem cells
$ n( T/ ?9 c5 h/ m- YEye development and blind cave salamanders( e! y. B+ F/ ~4 m) t: |
Skin, hair, and pigment stem cells. X, t* U8 ]+ M. p) O
13. Neural crest cells and axonal specificity
% j9 o! s w' X0 i. N6 C6 o9 ` n# D. iNeural crest cell specification and migrations
7 s6 Q, [4 ~0 s, D* wHead vs. trunk neural crest specification: f. K) e2 H* n
Neural crest-endoderm interactions forming facial structures, j" r5 x$ q* u* w0 Z* |0 p
Placode specification and separation
7 w% c; Z5 L3 L/ TTooth development and evolution
8 V, D+ {- y. X2 |- Y7 |Semaphorins, Robo, and ephrins in neural patterning- Y/ m; M# Z* O3 X2 i
14. Paraxial and intermediate mesoderm5 o' S! z2 m7 p! g. T: y
Specification of paraxial and intermediate mesoderm' y, z" G% V0 l& Q; }' e% \
Epithelialization of somites2 Z$ O! E; S0 H- Z" O2 r4 F
The syndetome—where tendons arise
4 \/ _- P3 k, H3 j C n6 ~. _FGFs, Notch, and Wnt in somite specification and separation
/ M7 O" l% m% U8 [The primaxial and abaxial musculature
4 |' A/ V2 @2 J, h8 C1 ~4 RNew sources of muscle precursor cells
& C. k' j$ g. S9 }' g, k( YPathways of skeleton formation! o4 \, d5 g" e
Regulating ureteric bud branching' a' Y/ p# @: Y3 B/ J5 r
Wnt and FGF proteins regulating nephron formation
% E |/ g0 U5 c) M: `5 Z9 U15. Lateral plate mesoderm and endoderm
) ^' f; ]+ s9 ^" |. Y# D4 ~Cloaca formation D, j+ _3 R3 w- w+ ~( T4 b/ B
Heart cell specification5 K' D6 s* E( s5 b+ s
Tbx genes, retinoic acid and heart chamber formation
$ p) L. l0 t1 J5 D- QHeart valve development
( c9 H' m2 M3 Y6 Q: ]7 HHematopoietic stem cells and their derivatives
. p4 G0 }: _ RLymphatic development1 T; o% Y) d' Q |1 v- }
Induction of arteries by neurons6 q% D/ g6 n/ o- m" Q/ x
Placenta as source of blood stem cells7 g. @, L- E" `
Adult blood stem cell niches4 h) Q+ ^: X# B& g/ D) E
Endoderm specificity4 l8 J: }& N- m/ U" q t5 d
Pancreas vs. liver development/ _) q1 Z1 d4 s7 q+ c# t+ l
Fate mapping pancreatic cells3 C% g* i& {# y! O c: p
16. Development of the tetrapod limb! p) [& v5 c6 c( }+ W" n
Hox code of limb development
) @- h2 L9 z1 p$ S3 vSpecification of the digits by hedgehog proteins and HoxD genes
/ y. M- f5 J- T% E2 Y9 h5 a4 OControversy over digit identities in dinosaurs and birds2 P. w# X* p/ r
Getting limbs from fins
9 u# h6 e$ E& B& t17. Sex determination
% V: n" `# e. d; JTiming and gene expression in mammalian sex determination
- m6 R( e2 W; S4 {; ?, LBrain sex determination pathways in vertebrates and flies- b( L$ G+ q* z' Q' e1 N! s8 Y
Hormone disruptors and sex determination problems x" @% U3 [' N7 }
Dosage compensation and sex determination+ J" M1 }7 g$ f) d( y3 F3 @ X
Temperature-dependent sex determination in turtles
! s5 [8 Q/ H6 C$ X3 U4 M& N18. Metamorphosis, regeneration, and aging( F7 b7 A% H$ x M4 S7 h; J7 Z
Molecular mechanisms of amphibian metamorphosis
8 Q* C+ _% a7 t: {- D0 m# G+ L' \Ecdysone receptors and the response to molting hormone! \. D" Z! ]8 W2 A: ?
Compartment formation in the wing imaginal disc. d4 l/ p- m" m0 Z: ?" T
Why can’t we regenerate our limbs?
) k/ T$ c8 l. w- E9 o9 d" a7 {; gNeuron- and mesenchyme-dependent stages of limb regeneration7 I6 T+ Q$ u* B0 b
Specification of limb regions by transcription factors during regeneration% D) K% G2 d9 V, D( T: D
Mitochondrial control of aging- ^# ] |- V2 [/ D2 [+ t# V1 M
Insulin pathway control of aging and possible relation to oxygen radicals
8 S" q- r' z; e8 U# B& }“Ageless” animals and environmental control of aging7 I/ W' c ?; I( X
19. The saga of the germ line8 G$ [, ~3 {5 U' ~
Genetic specification of germ-line cells in Drosophila and vertebrates! \' i/ w; D! ~! x1 m
Components of the Drosophila germ plasm
! {& I5 W2 O+ d+ r0 U$ jEgg and sperm stem cell niches in Drosophila/ {) Q& K( w- M& B% c; Q; i
Migration of primordial germ cells in mammals, chicks, and flies5 O4 T7 l d! h; S
Determination of meiosis and mitosis in C. elegans
7 H6 ^$ E- E9 ^4 c8 P9 m$ ORetaining mammalian spermatic stem cells1 C8 ]; ^; s w, }6 b3 t: i. v x" A
IV. Ramifications of Developmental Biology
; g& E; P6 ~; c( P3 ~20. An overview of plant development. B1 ]4 W. F9 V8 a
Gamete formation and pollen tube guidance% i' Z, c Z0 Y* a0 G, B/ E* c
Maternal effects and embryo development$ S% o; V& s0 t: H U( u
Radial and axial patterning
& ]* N+ V; w9 x! U6 O! t! bNew model for auxin specification of polarity: `" t* I) @! f* a6 Q8 F# O
Roles of microRNAs in plant development
9 w4 ?" ?9 a/ F5 @) \Dorsal–ventral leaf patterning
3 R- C+ v& V8 W7 W8 gLong-distance RNA transport and flowering& W; {3 g+ H- L6 ~! r% ^
Floral meristem specification
0 ^; B6 `6 i5 t0 H21. Medical implications of developmental biology
1 x5 ?: N3 }9 ^3 G" j- a& `Mechanisms of alcohol teratogenesis
" G5 [# P' L$ t7 HEffects of endocrine disruptors on human development0 J) X5 C) a& Z# x8 Y; _
Nutritional effects of gene methylation and disease susceptibility9 [2 B- t2 h. ~% I
Cancer as a disease of development' Y9 Q4 J* r' T( p$ g
Cancer stem cell hypothesis) _+ L1 U. N! G" ]9 w
Developmental approaches to cancer therapy
8 v" O# \0 n. q/ Z* z" F# tStem cell therapeutics
/ H; T2 ~! b/ F: j% J: p; j7 S& pRegenerating human limbs and neurons- F* O1 z+ D+ N- v% e; d
22. Environmental regulation of animal development
8 W! ?4 G2 G: }: g6 Y: H5 tMolecular bases for environmental regulation of gene expression
8 ?& A6 E3 a0 G( N• Importance of symbionts in mammalian gut and immune system
: ], r( Q( A$ w7 Z1 O$ M8 N7 Odevelopment
( N, o0 {9 W8 B: `Signaling from fetal mammalian lung to initiate labor/ k( k: H6 Y3 [0 a0 D7 X; u
The role of nutrition in the development of the dung beetle( M F: r1 M2 E3 k; m' z
Predator-induced polyphenism and toxicity testing
$ ] c1 _4 a2 Q$ p* d/ z L* {# V) R$ iGenetic assimilation of environmentally induced traits
' K" c# ~( Q5 Y23. Developmental mechanisms of evolutionary change o d: e+ N* M/ }4 u
Developmental modularity and evolution (stickleback studies)
; O" {! D1 ]! h# TEvolution by heterochrony, heterotopy, heterometry, heterotypy
# T6 [) q, R" HBMPs and Darwin’s finches7 R6 w& e: H H
Origin of neural crest cells and the origin of jaws
P0 a$ c' \& k: F+ ]! @. T) rThe search for the Urbilaterian ancestor |
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发表于 2009-9-25 02:27
发表于 2009-11-19 00:18
