PPT:Themes in B cell development (UCSF)

aspen

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Anthony DeFranco
( O6 r; q/ P# q' a  ~Department of Microbiology & Immunology, University of California at San Francisco% j9 P  s7 v) o# Q: B+ G

/ T/ x! a: v0 O! c7 P' rThemes include:
2 x% y$ k5 |0 x/ c0 I1 H7 A1. Checkpoints in B cell development:  feedback from Ig gene rearrangements. H( h9 ~4 h; Z+ @
2. Stromal environment/growth factors for B cell development
$ G* k4 a( Y' ~" k' r' u3. Lineage commitment:  transcription factors and Notch signaling
: B4 ]+ \: h5 X3 d4 b, S4. Central tolerance of B cells4 Q" _6 n1 g% {& U  G7 z
5. Peripheral tolerance of B cells2 u" m, X3 y4 S4 u1 K% r
6. 3 different types of mature B cells: choice of cell fate and relative roles

hualin840518

thanks

hughliang

非常感谢！
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rainsky1314

thanks very much !

刘子文

谢谢

beidouhan

好东西呢