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HSCs appear in the liver in the fetal stage. Researches usually start isolating HSC from fetal liver at Embryonic Day 14. HSC from fetal liver is highly cycling compared with the other types of HSC. The phenotypes of FL HSC can also be different. HSC also appears in fetal liver in human also. Some labs did use human fetal liver as a source for obtaining HSC, but not that common. |
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