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- 积分
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不要意思,我再发一遍,谢谢!!
7 \; Y% f$ J, |6 V1 b9 _$ h/ ^9 n1. Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases
3 V8 D! V% B1 x; C( V' L5 |4 |Dirk Hockemeyer, Frank Soldner, Caroline Beard, Qing Gao, Maisam Mitalipova, Russell C DeKelver, George E Katibah, Ranier Amora, Elizabeth A Boydston, Bryan Zeitler, et al.
1 \9 L( n6 \7 `; {3 HNature Biotechnology 27, 851-857 (13 August 2009) 9 ]$ S' i2 S2 p6 S8 V
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2. Targeted conditional gene knockout in human embryonic stem cells ! B. z1 {$ e7 V+ h3 B; U1 M5 ^
Lei Bu, Xiaolin Gao, Xin Jiang, Kenneth R Chien, Zhong Wang $ [, O9 ]2 H; t0 ]+ | K: R
Cell Research 20, 379-382 (9 February 2010)$ E( ^3 \& D0 c& F3 Z
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3. Gene Correction by Homologous Recombination With Zinc Finger Nucleases in Primary Cells From a Mouse Model of a Generic Recessive Genetic Disease 7 ~ \' F% i! m' v' p4 Z
Jon P Connelly, Jenny C Barker, Shondra Pruett-Miller, Matthew H Porteus $ c) m) {0 }* g" W0 y2 A1 V6 L A; ~
Molecular Therapy 18, 1103-1110 (13 April 2010) 5 [% e4 m3 _! u! Y: T8 a: y3 k- F4 ?
! f% h& S9 s) C$ t$ I" @4. Genome editing with engineered zinc finger nucleases 1 p$ }, u% R; s s8 W G7 |
Fyodor D. Urnov, Edward J. Rebar, Michael C. Holmes, H. Steve Zhang, Philip D. Gregory , _5 K/ A" m) b
Nature Reviews Genetics 11, 636-646 (September 2010) |
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