两篇关于生命本质的思考文献

tpwang

两篇俄国科学院物理学杂志上关于生命的review文章，供有兴趣的朋友参考。专注于具体方向研究的生物学家，也需要有更广阔的视野，并对生命本质及其哲学、物理和其他科学探索历史和现状有基本的了解。本站有朋友贴过E-薛定谔的经典文献What's life，这里的两篇2010年文章也有涉及。列出“内容”供参考。9 \( {0 y6 D# S  N- K/ L

/ J& |% b4 O% c$ G& T* A$ S/ j$ [How in the 20th century physicists, chemists and biologists answered the question: what is life?, Q7 R/ m) V3 Z) }8 ~( C
V P Reutov, A N Schechter
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Contents1 k$ M) X( v( r7 {
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1. Introduction+ D" n* V" P$ K* K
2. Main hypotheses concerning the origin of life on Earth
3 a' P% q, A( V4 W0 }$ r' ^3. We have failed to uncover something of major importance
! t& P/ O# g) k) C1 F3 w4. How to close the gap between knowledge and understanding?* N% p3 Z$ x' `( X
5. The data that served as the basis for the DNA model
1 @* e" g# k$ y# P: P3 P8 E6. The profound foresight of James Watson and Francis Crick  d4 I6 p/ ?. v* ^  C5 c, X3 A
7. Maurice Wilkins and Rosalind Franklin
! A! F) a: i0 Q0 q8. James Watson and Francis Crick
# L8 t1 ?( S  x9 ]8 }9. Is the knowledge of the DNA structure sufficient to answer the question `What is life'?
& A) R) {$ d# @& K% y10. N K Koltsov's idea of the matrix replication of biological molecules
0 x" X% b! i) ^3 X" C& ?3 E11. NWTimofeeff-Ressovsky's conclusion: a gene is a tiny compact structure & Y- L" }; \4 \( c
12. ``Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid''Ð a paper published in Nature
1 W* I/ M3 w; c6 q" c13. G A Gamow's idea of a universal code
$ ~6 g! r% W1 o% i* z- o4 \4 D14. Nobel Prize in Physiology or Medicine 1962 0 r1 ~; U8 h& B  ^; o) i
15. AMOlovnikov's idea of the role of telomeres in cell mitosis and the Nobel Prize in Physiology or Medicine 2009
) Y: a: j1 X1 J2 `0 d16. Prospects6 \3 c' }9 i5 M. r
17. Conclusions% A3 }! U# D& n" i+ b2 Y
18. Appendices
7 C3 F7 S' E* m, @( ^9 E' c" _9 j   I. Rosalind Franklin: talent and fate; - Z/ _: V+ m3 D) N1 e& B! k9 r
   II. James Watson, post-Nobel Prize;
, \$ ^, _$ p# N" E2 f   III. Francis Crick, post-Nobel Prize; # a# P7 N/ ?$ E) Q2 l
   IV. James Watson's lectures in Moscow in 2008;
6 A/ w8 A$ n) B. f: Y   V. What conclusions can we draw after analyzing the history of the discovery of DNA and James Watson's lectures?
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21st century: what is life from the perspective of physics?9 f' {6 x% D9 }/ n
G R Ivanitskii
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Contents, _: Q# P- ~0 \" o0 Y% ?' k
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1. Introduction
1 W+ e! o4 I2 \7 l2. Life. The problem of definition% t% F' M9 O+ Z* q" m
   2.1 The change in paradigm; + V1 y3 X" ]% |8 S6 p; H4 G% \
   2.2 The advent of new biophysical sciences (genomics, proteomics, metabolics); ' y( M8 ?  K- J3 |* y" ~7 x
   2.3 The evolutionary history of living organisms at a molecular level; 2 u* n0 G3 ^: O' n/ a
   2.4 Identification of factors accelerating the evolution of living systems;
8 B% v" ]* i  a   2.5 Borderline between living and nonliving matter
! v; C+ T) d3 B$ M, v/ E3. Interplay between living and nonliving matter (ten paradoxes)
1 ]& i, y  x" W4 z$ A. N8 f   3.1 Plato±Socrates' paradox;
6 d2 q" }3 ~7 Y, D5 k( p7 h5 V   3.2 Zeno's paradox; 1 c+ Q& e* }% x1 u% S
   3.3 Maxwell's demon paradox; # G3 V; G! o: z4 ~% t2 E; {
   3.4 Schrodinger's cat paradox;
* f0 P7 b  V0 ~* d: L   3.5 Stochastic ratchet paradox;
9 T* r8 M; B6 ]) C8 z- F5 ]   3.6 Paradox of time deficit; 8 O$ j* X' J% O" M/ g/ ^
   3.7 Paradox of homochiral structure;
1 Q& R. r2 h; t+ v9 n   3.8 Paradox of the part and the whole;
! u! E( u$ d& q  J! m! b8 e   3.9 Saint Petersburg paradox; . |9 Z1 u( h' W+ |* H
   3.10 Buridan's ass paradox
; N" G, H7 L+ \* C4. Discussion( C) y/ e% {; U" d2 u( J
5. Conclusion
2 h. o. X; S* f" B- T* }. GReferences
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