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举马里兰州干细胞研究委员会2011年资助项目三类别为例，9项由PI发起的独立研究项目；13例探索基金，资助年轻研究者或其他领域研究者，新手段、新模式、新机制项目；14位博士后资助。8 a# O: _3 |& U7 x$ |/ ]$ p
研究项目的资助也有明确的范围与目的，即可以导致一些特定难治疾病创新治疗方法的有前景项目，专门项目资助年轻研究者以及其他跨领域研究者，创新思路，培养博士后，鼓励与其他机构以及产业公司合作。
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This year’s MSCRF awards include:
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, F6 G0 H9 R! Q3 c9 Investigator-Initiated Research Grants (RFA-MD-11-01) – providing up to $200,000 of direct costs per year, for up to three years, to investigators with preliminary data to support their hypotheses;( W6 {4 B4 T1 |) m4 A! H" K5 t
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13 Exploratory Research Grants (RFA-MD-11-02) – providing up to $100,000 of direct costs per year, for up to two years, to new stem cell researchers (young investigators and scientists from other fields), for new approaches, mechanisms or models that may differ from current thinking in the field and/or new hypotheses that have little or no preliminary data; and0 Z o3 s3 V$ [% o; Z
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14 Post-Doctoral Fellowship Research Grants (RFA-MD-11-03) – providing up to $55,000 per year, for up to two years, including direct and indirect costs and fringe benefits, to post-doctoral fellows. , }1 \4 k% x3 ~9 G5 T, f
" A0 x' P" `. ^All MSCRF-funded research must be conducted in Maryland, and must involve human stem cells.5 A6 h) L- O7 V1 l! Y
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完整资助项目人与名称如下，尤其可以看看Exploratory项目和博士后项目，对学生们或有帮助：
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& I$ e3 j+ D, n7 q+ ]) Q2011 Awardees
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Investigator-Initiated Grant Awardees:" T5 H. p2 ]& U+ q, V$ Y Z) A
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Xu Cao
+ S" v* R ]* r5 \4 t6 T+ u MJohns Hopkins University- School of Medicine
0 p6 X4 n5 d5 g- L) k+ z"Stem Cell Recruitment in Anabolic versus Antiresorptive Osteoporosis Therapy”0 y: v: d4 J3 j a' h: H3 }" z) p
B6 w$ Y: z D7 j' `6 C# E
Linzhao Cheng
$ A) D* z% V9 J( t( _& w [9 FJohns Hopkins University- School of Medicine
! `5 h! W0 q/ e$ ]" I+ rIn collaboration with The California Institute for Regenerative Medicine (CIRM) & MaxCyte Inc. 9 V; d2 K7 M+ ^8 W Z1 u
"Red Blood Cell Production From Human IPS Cells Of Transfusion-Dependent Patients”2 r& _+ X7 J' n8 p, Y
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Mihoko Kai
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' i* p: c7 @( ]3 E8 T0 sJohns Hopkins University- School of Medicine
0 U9 D* W5 ?0 ^% c( c5 K) w7 Z. w; Y% ~$ z"Direct Generation of Human Dopaminergic Neurons By Defined Factors”3 t; J1 }7 Z9 a" j$ F
' g! g$ p: X. e" _& u1 J/ eVassilis Koliatsos; H, L9 W& x/ N+ t
Johns Hopkins University- School of Medicine
+ M+ i8 u. b3 {/ C: h1 \6 S) X3 RIn collaboration with The California Institute for Regenerative Medicine (CIRM) * w7 G8 v' @1 D4 L1 y
"Stem Cell Therapies in Animal Models of Traumatic Axonal Injury”8 y( E7 H& s! c# b& `* B( C
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Dara Kraitchman
: V* U! T* Y2 ^3 \$ cJohns Hopkins University- School of Medicine$ G* R2 B2 p: J( b3 t7 n/ h$ P' v
In collaboration with Surgivision, Inc.
6 q3 M) F; e1 w+ t. q5 k4 p"Single Cell Microencapsulation for Ischemic Heart Disease Therapy”0 c1 f: c2 y" W* t; \. k# |6 a# |" l5 H" X
# ^ P& ]" m ?. b6 x3 x( Z
John Laterra
6 m. K: c. h2 i% ]! I7 Y fHugo W. Moser Research Institute at Kennedy Krieger, Inc./ q" a" V% O- S9 u* b3 O1 e& A
"Regulation of Neural and Neoplastic Stem Cells by Kruppel-like Transcription Factors”- t O. w1 k0 X- D2 {
( y ]9 j. |" a& @. K" B7 }3 cFeyruz Rassool/ \7 P* Q# Z* ?1 \
University of Maryland, Baltimore - School of Medicine
% R' N5 v" o( T* I+ L"Remodeling the DNA Damage Response in Induced Pluripotent Stem Cells”+ N9 v6 r O6 P4 Z& B' P
6 o% Z7 Y) f8 n' {Piotr Walczak- x- k* g# M" _ z
Johns Hopkins University- School of Medicine
" u1 K; Z5 G: [6 H- w: S! @- r7 qIn collaboration with Q Therapeutics   Â
% j1 S( X$ D9 e3 [ M( Y1 b"Intra-arterial Targeted Delivery of Stem Cells to Brain Lesions Under MRI Monitoring”
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Elias Zambidis0 a* D; G1 ]3 n! _0 o7 x
Johns Hopkins University- School of Medicine
( T% S4 v/ u/ A- n/ ~3 `8 ~3 {In collaboration with Life Technologies, Inc.
/ n t0 L( k% k ?- d0 _$ ]" R"Clinical-Grade CD34-iPSC for Hematologic and Cardiac Therapies” 7 _1 j' U. }$ M B
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Exploratory Grant Awardees:
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( f7 a: Q( r* |% iMary Armanios 5 e0 g$ G7 H+ y! F
Johns Hopkins University- School of Medicine/ M$ R7 u* v U T& q9 l
"Telomerase in Ex Vivo Expanded Hematopoietic Stem Cells”0 U# |" q% }: V# s( r" O. A1 y
# T0 [+ N% T; [7 ~Visar Belegu- g- h* c1 C" U3 D# U
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
! x, v$ m% v$ w7 p"Differentiation of Fibroblast-Derived Induced Pluripotent Cells into Oligodendrocytes for Treatment of Neurological Disorders”
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4 |: y& ]( Y7 R" \/ p6 |Amy Belton' ?8 H4 Q" F8 y% S* Z
Johns Hopkins University- School of Medicine
/ E5 a' s6 M; l2 o"The Role of Hmga1 in Intestinal Stem Cells & The Generation Gut-Like Tissue”, n/ {& M9 {! P0 F8 ~2 o U
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Robert Brodsky( n6 E7 ~" h& `% R. [7 _
Johns Hopkins University- School of Medicine
' f% n# r3 `# O5 ]: X& `1 K3 t"A Preclinical Model of Acquired Aplastic Anemia Using Human iPSCs”
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Kan Cao
- y0 p; y+ b6 t; TUniversity of Maryland, College Park
, e' N l" i/ K/ \6 B- B: P"Induced Pluripotent Stem Cells as Models of Hutchinson Gilford Progeria Syndrome”
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5 [" z& Y2 J. g- q3 c8 p% TRaghothama Chaerkady
- {6 O6 _5 h- q3 OJohns Hopkins University- School of Medicine" v, @% c8 f/ m5 c
"Signaling Mechanisms Specifying Oligodendrocyte Development”
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Xiaochum Chen
. C# o( z! B1 Z: ]6 QUniversity of Maryland, Baltimore - School of Medicine $ \0 j$ A5 F3 }+ c) r
"Microrna Regulators of Ex Vivo Human Hematopoietic Stem Cell Expansion”
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Stephen Desiderio* O9 f' i4 j; r- W
Johns Hopkins University- School of Medicine
2 N+ q7 d: Q! l0 N, \& }0 s; M, A"Stromal Hedgehog Signaling In B Lymphoid Differentiation from Human ASCs”
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Shao Du$ `8 d; q) i; f. \
University of Maryland, Baltimore - School of Medicine
" ?& o! X+ a6 B; b8 T3 l"Reprogramming Of Satellite Cells & Human Mesenchymal Stem Cells For Muscle Repair”. r( _! u/ a2 d8 @' x3 T
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Koko Ishizuka, i6 F& X0 `" @. e
Johns Hopkins University- School of Medicine3 r4 t# P2 H A6 S
"Alteration in Neural Fate in Schizophrenia”1 D% s' o' k& i) I S; N& w7 J
/ e7 @1 x6 w. u7 X: rSaul Sharkis
( s! C. |0 R1 Z! ]- JJohns Hopkins University- School of Medicine6 S4 {* j0 y6 D) y; J: Q
In collaboration with Quality Biological, Inc.- ~8 j. ^, }& ~" O' o
"Human Stem Repair of Epithelial Tissue”' O; N1 s0 {8 j$ w1 l; u
. b+ z/ Z0 `( [( a( E4 P! CPaul Yarowsky5 X1 ~) t! i* Q# l& d! e, {9 U# p
University of Maryland, Baltimore - School of Medicine 3 W& l6 z3 C( l& r/ J
"Stem Cell Therapy for Traumatic Brain Injury”3 V5 B# g! A5 f+ K: [7 _/ w; P. e6 k
) i: M. Y9 b1 b( Z _& kZhaohui Ye
- b* O7 ^2 v& g& MJohns Hopkins University- School of Medicine
1 r# k( |9 X- M* Z& z! I2 D; S"Clinical Drug Screening Using Patient Specific Human iPSCs”
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Post - Doctoral Fellowship Grant Awardees:
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2 ?9 h* B/ N U2 V. BDian Arifin; D/ P( m1 o4 W, E
Johns Hopkins University- School of Medicine, N) l3 z7 E! C5 p
In collaboration with Pearl Lifescience Partners, LLC . r' [4 p u& c) f9 B1 ^- M+ G; `/ \ q
"Encapsulated Human Mesenchymal Stem Cells For Improved Islet Cell Therapy”
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William Brandt B @( f( G8 m# i4 s9 \
Johns Hopkins University- School of Medicine
R! i( R0 w& y. H0 n"Characterizing Notch Signaling in Bladder Cancer Stem Cells”
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Namshik Kim
\3 [4 g ^- y* p4 UJohns Hopkins University- School of Medicine+ r4 k o5 N8 x2 l
"Understanding The Role Of CYFIP1 Deletion/Duplication In Schizophrenia & Autism”. {5 f+ x. R/ X
! {$ X% O( ^9 [" w6 y+ A3 z
Julien Maruotti
( Z. a2 x/ w4 |9 |/ vJohns Hopkins University- School of Medicine
2 v& E. x$ |8 @' y4 ^' S5 J5 N% U0 i"A High Content Screen for Small Molecules that Promote Stem Cell differentiation into Retinal Pigmented Epithelial Cells for Potential Treatment of Age-Related Macular Degeneration and Other Retinal Degenerations”) f0 ^4 x! s" D* T4 [" z% w) V$ \
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Tammy Morrish* M8 I4 @% M& u9 O; W! x
Johns Hopkins University- School of Medicine0 k4 S0 L1 b' Z
"Telomere Recombination Mechanisms in Mesenchymal Stem Cells”
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" X' C4 l1 C' C( o6 b/ Y; g, |Amanda Phillips
9 |. H6 ?/ k* n& m! @, B8 O7 p4 XJohns Hopkins University- School of Medicine
" ~, x% Q' Y# _0 i5 K* x- V& o9 z"Focal Transplantation of Human Neural Stem Cell-Derived Astrocytes Isolated From Als Patients into the Rat Spinal Cord”. u" Z0 _ W4 l6 x* U% Q
( y! f- F; I8 QPrakash Rath
2 P+ O& @8 R5 @- IHugo W. Moser Research Institute at Kennedy Krieger, Inc.
) z& a; ~# ] v& o7 a% v"Modulating HGF/c-Met Signaling in Human Normal and Neoplastic Stem Cells”* ~: w: ?$ ~" Q; Y" V7 R# r( X) Z
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Sandeep Shah
M6 J( m/ T6 C1 jJohns Hopkins University- School of Medicine X5 T8 B7 ` [2 Y$ @0 w
In collaboration with Life Technologies, Inc.
# c2 P5 O0 _4 S% `$ ?: ~: `( N"HMGA Proteins in Stem Cell Survival and Induced Pluripotency”
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Shobana Shanmugasundaram
0 {+ n; b" p5 p- B: `University of Maryland, Baltimore - School of Medicine % L; v, _3 D$ e7 n* Q
In collaboration with Biosurface Engineering Technologies, Inc.  Â
8 Q% Z5 \( R" w3 K# W/ V& Q4 z- a) W"Optimization of the 3D Scaffolds with Enzyme and Peptide for Osteogenic Differentiation in Stem Cells”
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4 t. j) ?1 \6 t4 D" A! k, @Yang Song. `! Y$ c; o0 W9 A
Johns Hopkins University- School of Medicine/ E+ \8 g+ `$ ?& Y7 m0 G" m
In collaboration with Innovative Biosensors, Inc.: V3 i7 N6 |3 o, w9 N
"Signals Cooperating with RUNX1 to Specify Adult HSC from hESC”
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0 d: U e* U1 ]6 BJuan Song% t1 F6 c6 H6 ]3 t. a; A; s- ~/ m
Johns Hopkins University- School of Medicine7 Z; c, B, ]$ s1 V6 Q
In collaboration with Life Technologies, Inc.
9 R4 ^( e0 o8 _" ~+ p4 i- s, {"Understanding the Mechanism of a Schizophrenia Susceptibility Gene Disc1 in Regulating Synapse Development Using Patient-Derived iPSCs”
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Yijing Su
" I7 S9 T) K! T( ZJohns Hopkins University- School of Medicine
l- q# Z) M0 r" J, q& t- _"Roles of Tet Proteins In Regulating DNA Demethylation And Differentiation of Human Pluripotent Stem Cells And Neural Progenitors”
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Chiaochun Joanne Wang
1 e/ z" Y0 o# {* Z! v4 i7 PJohns Hopkins University- School of Medicine; p: T/ ?! P: s/ D" P+ B+ [' |
"Microvasculature Mimicking Microfluidics for High-Throughput Screening of Targeted and MR Trackable Stem Cells”
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5 i9 _5 [' ]" O$ W1 dShuming Zhang" T3 U4 p, Z4 k% n0 K
Johns Hopkins University- School of Medicine6 \+ Q, K9 s; t/ Z# U
"Role of Electrical Stimulation on Differentiation of Human iPS Cells and iPS-Derived Neural Crest Stem Cells” |
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发表于 2011-5-27 21:59
