重编程技术革命——niche reprogramming

sunsong7

突破：病人体细胞及肿瘤细胞长期体外培养 http://www.stemcell8.cn/thread-51419-1-1.html
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补充内容 (2012-1-14 14:19):
$ P3 M+ y: z* ?0 A9 f6 B1 S4 V平衡维持:造血祖细胞与niche及分化子细胞间的“对话”  http://www.stemcell8.cn/thread-51289-1-1.html
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sunsong7

再有新进展：  P# r  ^+ s/ a+ n
科学家首次将脐带干细胞转化为脑支持细胞！http://www.stemcell8.cn/thread-51562-1-1.html
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sunsong7

iPS现原形——日本人培育出癌症干细胞 http://www.stemcell8.cn/thread-54789-1-1.html
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JOEL

回复 sunsong7 的帖子! Z+ ~, d( h7 s5 S: f) R+ z, @
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Thanks for sharing this interesting in formation.& k0 ]& S5 j" E: G4 Q/ C' A
If the theory really worked in the way that cancer is not a result of the so-called genetic mutation but a consequence of niche reprograming it would mean that 1) the evironment out of the nucleus and 2) the environment out of the cell and 3) the natural environment, i.e. macro-environment, have been playing a decisive role. And it would be a revolutionary finding that guides the anti-cancer research into a new stage!8 K0 r$ e) t* n2 I( d! b
To control the both micro-and-macro-environments, i.e. to stop the interaction between the micro-and-macro-enviroments will be the focus for against cancer. Or frankly, the key is how to stop the niche reprograming by barring any factors as the necessary conditions enviroments out of the nucleus. Mama mia it is still a great project!

JOEL

回复 sunsong7 的帖子: ?" @/ J  Q- _8 c. N  j- P+ `, X
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Quotation ------"子曰：上善若水 大成若缺  干细胞治疗的终极解决方案就是不使用外源干细胞（cell-free is the final solution of stem cell therapy ）"* H6 }5 b! y! ]# [- h& @
This is wisdom!

626630192

回复 zyyzyy1985 的帖子
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好文章

wangji5

这篇帖子好多精彩文献啊！！学习学习！！

sunsong7

日本美女科学家研制新型万能细胞STAP  http://www.stemcell8.cn/thread-76112-1-1.html: J5 L. `# D7 q4 w
日本诱导干细胞研究再次发威（附原文） http://www.stemcell8.cn/thread-76054-1-1.html) U& S9 z4 ?. T% O- q

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sunhongmei

非常感谢！只是现在还下载不了，包包不够。继续努力

abgg

观念上提出假说，假说有一定的合理性，但如何证明或证伪这个假说并不容易。重编程过程的捕捉还是需要一系列技术突破的。