Adult mouse bone marrow stem cells can become cells of the nervous system

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日期: 2003-08-19 今日/总浏览: 1/435. Y. @8 E+ u( D4 B/ g

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4 ^) s$ y8 y8 `1 A# RUniversityofMinnesotaresearchersshowthatadultbonemarrowstemcellscanbeinducedtodifferentiateintocellsofthemidbrain.Thefindings,publishedintheonlineearlyeditionoftheProceedingsoftheNationalAcademyofSciences,suggestthatadultbone-marrow-derivedstemcellsmayonedaybeusefulfortreatingdiseasesofthecentralnervoussystem,includingParkinson'sdisease.7 H' ?4 ?5 O- U& X  W
Thepotentialoftheseadultstemcells,termedmultipotentadultprogenitorcells(MAPCs),werethesubjectofresearchreportedinNatureinJune2002.Today'spublishedresearchfindingsshowspecificcelldifferentiationforaspecificgoal.Whilethistypeofcelldifferentiationhasbeenshowntooccurfromembryonicandneuralstemcells,thisisthefirsttimeadultbone-marrow-derivedcellshavebeenshowntogeneratedopaminelikeneurons.
+ o9 e0 S: A$ X# v) V& _We'reabletoshowinvitrogenerationoffunctionaldopamineproducingcellsfromadultbonemarrowstemcellsneededfortherapyofParkinson's,saidleadinvestigatorCatherineVerfaillie,M.D.,directoroftheuniversity'sStemCellInstitute.ThisfurtherprovessimilarityoftheMAPCswithembryonicstemcells.# K* s. T/ ^$ E" F: ^8 \# B$ p
Again,whileadultstemcellsholdgreatpromise,sidebysidecomparisonofadultandembryonicstemcellsmustbedonetodeterminewhichstemcellsaremostusefulintreatingaparticulardisease,saidVerfaillie.% u6 h6 w* O3 S7 k

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作者: 0 ?4 k. y6 A) o
来源: University of Minnesota) |3 t0 P' o# o( t  v- A
发布者: 亦云