Slide No. | Slide Titles |
| Launch Pathway |
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back to top | APOPTOSIS AND CELL CYCLE | |
1 | Programmed Cell Death | |
2 | Activation and Inhibition of Apoptosis | |
3 | Mitochondria in Apoptosis | |
4 | ATM/p53 Signaling Pathway | |
5 | Caspase Cascade | |
6 | Caspase Activation Intrinsic Pathway | |
7 | Granzyme B | |
8 | Fas and Related Proteins with Death Domains | |
9 | Fas Signaling Pathway | |
10 | G1 and S Phases of the Cell Cycle | |
11 | G2 and M Phases of the Cell Cycle | |
12 | Regulatory Cascade of Cyclin Gene Expression | |
13 | The p53 Signaling Pathway | |
back to top | CYTOKINES, GROWTH FACTORS AND HORMONES | |
14 | Cytokines, Growth Factors and Hormones | |
15 | Structures of Activin and Inhibin Prototypes and Precursors | |
16 | Structures of Three Chemokine Receptors | |
17 | Angiopoietins and their receptors, Tie1 and Tie2 | |
18 | EGF Receptor Signal Transduction Pathway | |
19 | Transmembrane Precursors of EGF Family Members | |
20 | Possible Receptor Combinations and Ligand–binding with EGF and HGF Families | |
21 | Actions of Flt-3/Flk-2 Ligand on B Cell Lymphopoiesis in Bone Marrow | |
22
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23 | IGF Regulation of Apoptosis | |
24 | IL-13 and IL-4 receptor combinations and binding | |
25 | IL-18 Production and Role in Immune Response | |
26 | Neurotrophins and Their Receptors | |
27 | TrkA Receptor | |
28 | GDNF Family with Receptors | |
29 | PDGF Receptors and Actions | |
30 | Signaling Pathway of TGF-b | |
31 | Bone Morphogenic Protein | |
32 | TNF Signaling Pathway | |
33 | TNF-α and TNF-β (LT) Forms and Receptor Binding | |
34 | Proposed Balance Between TNF Superfamily Members in Relation to Bone Formation or Destruction | |
35 | Structure of Receptors and Growth Factors Involved in Vasculogenesis, Angiogenesis and Lymphomagenesis | |
36 | VEGF Receptor and Ligands | |
37 | Signal Transduction Pathways Involved in Prolactin Regulation | |
38 | Insulin Pathway | |
39 | Glucocorticoid Receptor Signaling | |
back to top | CYTOSKELETON AND EXTRACELLULAR MATRIX | |
40 | Vascular Endothelial Cell Interactions and Signaling | |
41 | Integrin Signaling in Cell Survival and Death | |
42 | VEGF Receptor Signaling | |
43 | The MMP/Cytokine Connection | |
44 | Events Leading to Angiogenesis and Metastasis | |
back to top | GENE REGULATION AND EXPRESSION | |
45 | Transcription Factor Regulation (CREB, Elk-1 and c-Fos) | |
46 | Hormonal Targeting of Nuclear Complexes to Chromatin | |
47 | The Jak/Stat Signaling Pathway | |
48 | STAT3 Signaling Pathway | |
49 | PPAR Signaling Pathway | |
50 | Formation of Nucleosomes | |
51 | DNA Compaction into Chromosomes | |
52 | Early Response Events to Moderate Double Strand Break (DSB) Levels | |
53 | Cell Cycle Checkpoint and Double Strand Breaks (DSB) | |
54 | Linkage Between DNA Repair and Chromatin Modification | |
55 | Hypothetical Model on the Functions of the WRN, BLM and MRE11 | |
56 | mRNP Transport through the Nuclear Pore Complex (NPC) | |
57 | Cargo Import by the Importinα-Importinβ Pathway | |
58 | Modular Structure of Transcription Factors | |
59 | Transcription Activation by Nuclear Receptors | |
60 | Coupled RNA Splicing and Nuclear Export | |
61 | RNA Polyadenylation | |
62 | Mammalian mRNA Polyadenylation Machinery | |
63 | RNA Maturation | |
64 | RNA-guided Epigenetic Control of Gene Expression | |
65 | Phosphorylation-driven Regulatory Switch from Transcription Initiation to Elongation | |
back to top | G PROTEINS AND CYCLIC NUCLEOTIDES | |
66 | Cyclic Nucleotide Metabolism - cAMP | |
67 | Cyclic Nucleotide Metabolism - cGMP | 7 \, A @+ O4 _' O7 u) o" ]
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68 | Diversity of G-Protein-Coupled Receptor Signal Transduction Pathways | |
back to top | IMMUNE CELL SIGNALING AND BLOOD | |
69 | T Cell Receptor (TCR) Signaling | |
70 | B Cell Receptor Complexes | |
back to top | ION CHANNELS | |
71 | Monovalent Ion Channels | |
72 | Activation and Inactivation of the Sodium Channel | |
73 | Ligand-Gated Ion Channel: Structure and Activation Status | |
74 | Aquaporin Channel Structure | |
75 | Calcium Channel Structure | |
76 | Calcium Channel Pore Region | |
77 | Schematic Representation of the Chloride (CIC) Channel | |
78 | Schematic Representation of the HCN Channel | |
79 | 2TM Potassium Channel Structure | |
80 | 6TM Potassium Channel Structure | |
81 | Sodium Channel Structure | |
82 | Sodium Channel Pore Region | |
back to top | LIPIDS IN CELL SIGNALING | |
83 | PTEN Pathway | |
84 | Lipids in Cell Signaling | |
85 | Inositol Phosphates | |
86 | Phosphatidic Acid Synthesis | |
87 | Signaling by Inositol Phospholipids | |
back to top | MULTI-DRUG RESISTANCE | |
88 | Mechanisms In Multi-drug Resistance: ABC-transporters and detoxification enzymes I hepatocytes | |
89 | ABC-ATPases as Regulatory Transporters for NHRs: chemical sensors for endogenous metabolites and xenobiotics | |
90 | Domain Organization of Bile Salt Transporter (BSEP) | |
91 | Domain Organization of Multi-drug Related Protein (MRP1) | |
back to top | NEUROBIOLOGY | |
92 | b-Amyloid Plaques | |
93
) t! T i8 E9 M/ s | New Notch-γ-Secretase | |
back to top | NEUROTRANSMISSION | |
94 | Second Messenger Systems Involved in Reward and Addiction | |
95 | Limbic Reward Circuit | |
96 | Major Noradrenergic, Dopaminergic and Serotonergic Pathways in the CNS | |
97 | Intracellular Signaling Pathways Activated by Endothelins | |
98 | NPY Inhibition of Catecholamine Release | |
99 | Ascending Pain Pathway | |
100 | Modulation of Pain Transmission | |
101 | Mechanism of Action of Selective Monoaminergic Reuptake Inhibitors. Figure A | |
102 | Mechanism of Action of Selective Monoaminergic Reuptake Inhibitors. Figure B | |
103 | Drug Activation of Dopaminergic Neurons | |
104 | Schematic Representation of the GABAB Receptor | |
back to top | NITRIC OXIDE AND CELL STRESS | |
105 | Oxidative Stress | |
106 | Neuronal Nitric Oxide Synthase (nNOS) | |
107 | Endothelial Nitric Oxide Synthase (eNOS) | |
108 | Inducible Nitric Oxide Synthase (iNOS) | |
109 | Nitric Oxide Metabolism | |
110 | Proteasome/Ubiquitination | |
111 | Formation of Activated 20S Proteasome | |
112 | Ubiquitin-Proteasome Pathway | |
back to top | PROTEIN PHOSPHORYLATION | |
113 | Mitogen-activated Protein Kinase Cascades |
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114 | Akt Signaling |
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115 | Signaling Pathways Activated by VEGF | ! G9 g6 Q* G( f, l+ P& I; i
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