求解

changbo529

最近小弟在看一篇有关神经干细胞（球）迁移的文献时，发现文献中涉及有神经球迁移过程的长度和宽度这两个概念，麻烦哪位前辈指导一下怎么界定神经球迁移的长度和宽呀？谢谢

changbo529

moderately crosslinked Gtn-HPA hydrogels (i.e . GH-1.0 and GH-1.2),0 n7 C5 D9 x3 H5 o- e' v8 e( P
these processes contained multiple nuclei along their length and: X* R. n) q7 F5 Q4 b
were likely to be migratory chains of young neurons ( Fig. 4B eC). On
5 Z: B7 c) D5 C" o3 Sthe other hand, processes in the heavily crosslinked Gtn-HPA# ?( _$ w; |  ^' O( h: ]
hydrogels (i.e., GH-1.7) did not contain any nucleus and were
# l8 v$ Q8 K$ D% w, D! v; `2 K  _" dneurites extending from the neurospheres (Fig. 4D). This was also
- ^8 k: H  k. K. T; }) {re fl ected in our measurements of process length and particularly,( u( x: T0 ?# Z4 y
process width, which gave a strong indication if entire cells were
. C. h0 M, l+ O2 @" J; p6 L; Tpresent in the process. One-factor ANOVA revealed signi fi cant+ v) I; e9 \+ ^9 `# p
effects of crosslinking degree on both process length (p < 0.0 0 01,1 h) H% d# e% t, a& l$ a. j
power &frac14; 1) and width ( p < 0.0 01, power &frac14; 0.998) (Fig. 4E and F).
" |6 z( [( {, D. a# h/ Z  oBetween GH-1.0 and GH-1.2, the increment in crosslinking did not
6 _) b+ L( V& x" A. d2 r" [3 naffect the process width but caused a reduction in process length
4 n  O0 ]2 A5 r(Fisher’ s post-hoc test, p < 0.05). This agreed with the immuno-staining fi ndings that the increment in crosslinking from GH-1.0 to
6 G5 D9 z/ a) }% K0 p9 D' TGH-1.2 did not prevent chain migration from occurring but did
6 H8 \7 ^4 @! s, limpede the extent of migration of the immature neurons along
) C0 I- `" B) l1 V+ ^these chains. On the other hand, between GH-1.2 and GH-1.7, both4 Q7 I7 @( b3 v. E5 i1 T
process length and width were signifi cantly reduced (Fisher’ s post-hoc test, p < 0.0 01). This was also in line with the immunostaining# _! v" n+ H+ ]- f
fi ndings that further increment in crosslinking from GH-1.2 to GH-1.7 eliminated chain migration and only permitted the formation of
7 \% V3 y7 }6 j- cneurites.
1 X1 M  m- \# T& y3.5. Influence on