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本帖最后由 细胞海洋 于 2012-10-16 13:24 编辑
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16 October, 2012 Volume 22, Issue 4
6 A+ S+ I4 d( J On the cover: Cancers sharing the same clinical diagnosis often harbor striking differences at the molecular level. Such is the case for diffuse large B cell lymphoma (DLBCL). A careful examination of different DLBCL molecular subsets reveals distinct metabolic signatures. Depicted here is a close-up of an “OxPhos” cancer cell with pink mitochondria visible below the plasma membrane. Callouts in gray highlight the integrated approach used to reveal differences in carbon utilization, mitochondrial proteome, fatty acid oxidation, and glutathione levels in this DLBCL subtype. See Caro et al., pp. 547–560. Cover credit: Benjamin Szlyk and Illana Stanley.
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