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"We've been led to believe that, since so many different antigens have to be made, APCs need a large, diverse set of activities," says Mellman. But dendritic cells (DCs) and B cells are no more endowed with lysosomal proteases than is the average fibroblast, based on the new results. Of the APCs tested, only macrophages were particularly protease packed.# |; K: K! C9 }
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Reference:
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* C+ u9 r: ]+ P, _- IDelamarre, L., et al. 2005. Science. 307:1630–1634.(Smart antigen-presenting cells (APCs) us) |
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发表于 2009-3-6 08:42
发表于 2015-6-6 11:17
